Evaluation of the interrelationship between inflammatory markers, rosacea, ocular symptoms, and migraine comorbidity.

Rosacea is a chronic skin condition linked to ocular symptoms and migraines. This study compared inflammatory and hematological markers in rosacea patients and healthy controls. A total of 150 rosacea patients participated, matched by age and gender with controls. Researchers collected demographic and routine hematological data from all participants. Neurological evaluations assessed headache and migraine prevalence. Ophthalmological examinations were performed on rosacea patients to evaluate ocular involvement. Results showed rosacea patients had higher white blood cell counts, 7.22 versus 6.83. They also had higher neutrophil counts and lower eosinophil counts. Mean corpuscular volume and red cell distribution width-standard deviation were lower in rosacea patients. Mean corpuscular hemoglobin concentration was higher in rosacea patients. Headaches and migraines were more common in rosacea patients than in controls. Ocular symptoms were present in 51% of rosacea patients, especially in females and those with migraines. Clinical relevance: This research indicates that rosacea patients often experience higher rates of migraines and ocular symptoms, highlighting the importance of comprehensive evaluations for better management.