MigraineMind research summary

Evaluation of Ocular Higher-Order Aberrations in Patients with Migraine: A Comparative Study.

Rom J Ophthalmol | 2026

Observational study
AuthorsMishra AK, Shukla R, Garg P, Shukla A, Shukla M
JournalRom J Ophthalmol
Publication year2026
PubMed ID42572641

Summary

This study examined how migraines affect eye functions, specifically higher-order aberrations (HOAs). Researchers compared 99 migraine patients with 99 healthy individuals. They measured various eye distortions using advanced equipment. The migraine group included both episodic and chronic patients. Results showed that migraine patients had higher total HOAs. However, this difference wasn't statistically significant when compared to healthy controls. Notably, two specific types of aberrations, coma and oblique trefoil, were more common in migraine patients. The oblique trefoil aberration was significantly higher in migraine cases compared to controls. Understanding these differences could help in identifying how migraines affect vision. This research highlights potential links between migraines and eye health. Future studies could explore how treating migraines might improve visual distortions. Overall, the findings suggest a need for further investigation into the eye-related aspects of migraines and their impact on patients’ quality of life. Clinical relevance: This research indicates that specific eye distortions in migraine patients may guide better treatment options and improve overall patient care.

Key Learning Points

  • Migraine patients may experience specific eye distortions that differ from healthy individuals, which could impact their vision and quality of life.
  • Higher-order aberrations, particularly coma and oblique trefoil, were more prevalent in migraine patients.
  • The oblique trefoil aberration was significantly more common in migraine patients compared to healthy controls.
  • Understanding the relationship between migraines and eye health could lead to improved treatment strategies for patients.
  • Future research may explore how effective migraine treatments could alleviate visual distortions associated with the condition.

Research Informatics

CROSS-SECTIONAL STUDY

Higher-order aberrations linked to chronic migraine.

exposureMigraine
conditionMigraine
comparatorHealthy controls
populationMigraine patients and healthy controls
sample Size198
main OutcomeHigher-order ocular aberrations

Original research

Read the original publication and review its full methods and findings on PubMed.

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