EEG microstate responses of migraine patients to transcutaneous electrical nerve stimulation.

Migraine patients show distinct patterns in their brain activity, known as EEG microstates. This study looked at how these patterns change with treatment using transcutaneous electrical nerve stimulation (TENS). Fifty-one migraine patients participated, with some receiving real TENS and others receiving a sham treatment. Researchers examined the patients' brain activity while they rested. They focused on four specific types of EEG microstates, labeled A to D. The results revealed that TENS treatment altered the brain's microstate patterns compared to the sham group. This suggests that TENS may influence how migraine patients' brains process information. Understanding these changes could help improve treatments for migraine sufferers. The study opens new avenues for research into how brain activity relates to migraine symptoms and treatments. Overall, TENS might offer a beneficial therapeutic option for managing migraines effectively. Clinical relevance: This research indicates that TENS may positively affect brain activity in migraine patients, potentially leading to enhanced treatment strategies for managing migraine symptoms.