Interictal cognitive event-related potentials in migraine subtypes: association with neuropsychiatric symptoms.

Migraine patients often report cognitive decline, impacting their daily lives. This study examined cognitive event-related potentials (CERP) in different migraine subtypes. Researchers analyzed 173 participants, including those with migraine without aura, migraine with aura, and migraine aura without headache. They compared these groups to healthy controls. The study measured N200 and P300 latencies and amplitudes, which are important for cognitive processing. Results showed that patients with migraine without aura had longer N200 and P300 latencies and lower P300 amplitudes than healthy individuals. Patients with migraine with aura and those with migraine aura without headache also had prolonged latencies. These findings suggest that different migraine types affect cognitive function differently. Understanding these differences may help improve treatment options for migraine patients experiencing cognitive issues. This research highlights the need for further exploration of cognitive symptoms in migraine. Clinical relevance: This study indicates that cognitive dysfunction varies among migraine subtypes, suggesting tailored treatment approaches may be beneficial for managing patients' cognitive symptoms.