Patient Preferences Toward CGRP-Targeting Preventive Migraine Treatments in Japan: Discrete Choice Experiment.

This study looked at Japanese patients' preferences for migraine treatments. It focused on new options called CGRP-targeting therapies, which include gepants and monoclonal antibodies. Researchers wanted to understand what treatment features mattered most to patients. They used a method called a discrete choice experiment (DCE) to gather data. First, they reviewed literature and clinical trials to identify key treatment attributes. Then, they held a focus group with five patients to ensure clarity and gather more insights. After refining their questionnaire based on this feedback, they conducted an online survey with eligible patients. The survey took place in May and June 2025. This research is important because it helps identify what patients value in migraine treatments. Understanding these preferences can guide the development of more effective therapies that align with patient needs and expectations. Clinical relevance: This research highlights the importance of patient preferences in developing effective migraine treatments. Understanding these preferences can lead to more tailored therapies that improve patient satisfaction and outcomes.