Acupuncture at Zuqiaoyin (GB44) Modulates Regional Brain Activity in Migraine Without Aura: A Resting-State Functional Magnetic Resonance Imaging Study.

Migraine is a common neurological disorder affecting many people. This study examined acupuncture at a specific point called Zuqiaoyin (GB44). Researchers wanted to see how effective this treatment is for migraine without aura. They compared it to acupuncture at nonacupoints, which served as a control. The study included 20 patients with migraine without aura. Twelve patients received acupuncture at GB44, while eight received sham acupuncture. Both groups underwent ten acupuncture sessions over one month. Researchers used a visual analogue scale (VAS) to measure pain levels. They also performed resting-state functional magnetic resonance imaging (fMRI) to study brain activity. The findings could help clarify how acupuncture affects the brain in migraine treatment. Overall, acupuncture at GB44 showed promise in reducing migraine symptoms and altering brain activity, suggesting it may be a beneficial treatment option for patients. Clinical relevance: This research indicates that acupuncture at GB44 may effectively reduce migraine symptoms and improve brain function, offering a potential treatment option for patients with migraine without aura.