Systemic immune-inflammation index and prognostic nutritional index in vestibular migraine and Meniere's disease: a retrospective comparison with healthy controls.

This study compared the systemic immune-inflammation index (SII) and prognostic nutritional index (PNI) in patients with vestibular migraine (VM), Meniere's disease (MD), and healthy controls. It included 100 patients from each group. Researchers used routine blood tests to calculate SII and PNI. They also looked at how these indices related to the frequency of vertigo attacks and dizziness-related disability. The results showed no significant differences in SII and PNI among the three groups. However, patients with VM experienced more annual vertigo attacks than those with MD. This difference was statistically significant, indicating that VM may have a higher impact on patients' lives. The study suggests that while SII and PNI are not useful for distinguishing between these conditions, the frequency of vertigo attacks can help in understanding the severity of VM compared to MD. Clinical relevance: This research indicates that vestibular migraine may cause more frequent vertigo attacks than Meniere's disease, helping clinicians assess and manage these conditions more effectively.