Mitochondrial migraine: A multicenter study based on mitochondrial diseases presenting as encephalopathy and/or myopathy.

This study looked at migraine in patients with mitochondrial disease (MD). Mitochondrial diseases affect how cells produce energy. The researchers wanted to see if migraines are linked to mitochondrial problems. They studied 48 patients with MD who also had encephalopathy or myopathy. These patients came from seven medical centers in China. The study took place between January 2020 and March 2023. The researchers used a structured questionnaire to gather important information. They collected demographic data and detailed headache information. The study found that migraines were common among these patients. This suggests that there may be a connection between migraines and mitochondrial dysfunction. Understanding this link could help explain why some patients have migraines. It may also lead to better treatment options for those suffering from both conditions. Overall, the findings highlight the importance of studying migraines in patients with MD. Clinical relevance: This research suggests that migraines may be a common issue in mitochondrial disease patients, potentially guiding tailored treatment strategies for better management of their symptoms.