A Clinical Study of Retinal Nerve Fibre Layer and Ganglion Cell Layer changes in patients with Migraine at a Tertiary Care Hospital.

This study looked at changes in the eyes of migraine patients. Researchers compared the thickness of the retinal nerve fibre layer (RNFL) and ganglion cell layer (GCL) in 100 migraine patients and 102 healthy controls. The patients included 33 with chronic migraines and 67 with episodic migraines. They used a special eye test called OCT to measure these layers. The study found that migraine patients had thinner RNFL compared to healthy individuals. Specifically, chronic migraine patients had more significant thinning in certain areas of the RNFL. Most patients reported photophobia and ocular pain as common symptoms. This research helps us understand how migraines may affect the eyes. It suggests that eye changes could be linked to migraine severity and type. These findings may lead to better ways to diagnose and treat migraine patients in the future. Clinical relevance: This study indicates that eye layer changes in migraine patients could assist in diagnosis and treatment strategies, potentially improving care for those with chronic and episodic migraines.