Association between migraine and angiogenic biomarkers in women with suspected or confirmed hypertensive disorders of pregnancy.

Migraine is linked to higher chances of developing hypertensive disorders during pregnancy. Researchers studied how migraine affects certain biomarkers in pregnant women. These biomarkers include soluble Fms-like tyrosine kinase-1 (sFlt-1) and placental growth factor (PlGF). Elevated sFlt-1 and low PlGF can indicate serious pregnancy complications. The study involved women with suspected or confirmed hypertensive disorders of pregnancy (HDP). Researchers measured the levels of sFlt-1 and PlGF in these women. They also checked for migraine diagnoses before and during the pregnancy. The goal was to understand how migraine relates to these biomarkers. Results showed that women with migraines had different biomarker levels compared to those without. This suggests that migraine could impact the risk of complications during pregnancy. Understanding these relationships may help in managing pregnancies at risk for hypertensive disorders. Clinical relevance: This research highlights the need for monitoring migraine in pregnant women with hypertensive disorders.