Middle Meningeal Artery Embolization Using Non-Adhesive Liquid Embolic Agents for Chronic Resistant Migraine: Interim Feasibility and Safety Analysis of a Prospective Single-Arm Trial.

Chronic resistant migraines are difficult to treat with standard therapies. Researchers are exploring a new method called middle meningeal artery (MMA) embolization. This method targets specific nerves linked to migraine pain. In this study, ten patients underwent this procedure using non-adhesive liquid agents. The study included patients who met specific criteria for resistant migraines. Out of 318 patients screened, only 16 qualified. The procedure was performed between October 2024 and November 2025, with data collected until September 2026. Researchers focused on the technical success of the procedure, using a special grading scale. Early results suggest that this method may be safe and feasible for treating chronic migraines. More research is needed to confirm its effectiveness. This could provide new hope for patients suffering from chronic migraines that do not respond to existing treatments. Clinical relevance: This research indicates that MMA embolization may offer a new treatment option for patients with chronic resistant migraines, potentially improving their quality of life.