MigraineMind research summary

The role of the corrugator supercilii and its impact on the evolution of migraine medicine: A narrative review.

Headache | 2026

Review
AuthorsBlumenfeld A, Pasao KA
JournalHeadache
Publication year2026
PubMed ID42985862

Summary

the corrugator supercilii," and "botulinum toxin injections." Researchers found that injecting botulinum toxin into the corrugator supercilii muscle can reduce migraine frequency. This muscle plays a key role in headache medicine. It is linked to important nerves involved in pain pathways. The study highlights the muscle’s historical significance in developing migraine treatments. It also discusses potential complications from injections and emerging clinical implications. Understanding the anatomy and function of this muscle can improve treatment strategies. The research emphasizes how aesthetic procedures can lead to effective migraine therapies. The findings suggest that botulinum toxin can be a valuable option for chronic migraine sufferers. Overall, this study provides insights into the evolution of migraine medicine and the role of the corrugator supercilii muscle in treatment. Clinical relevance: This research highlights the corrugator supercilii muscle's importance in migraine treatment, suggesting that targeted injections may enhance therapeutic outcomes for patients suffering from chronic migraines.

Original research

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