MigraineMind research summary

Functional neurological disorder and migraine: a cross-sectional health-related quality of life study.

J Psychosom Res | 2026

Observational study
AuthorsFrança M, Cabral M, Abreu P, Cabreira V, Dias R
JournalJ Psychosom Res
Publication year2026
PubMed ID43008500

Summary

This study looked at how functional neurological disorder (FND) and migraine affect quality of life. Researchers studied 68 patients, with 27 having FND and 41 experiencing migraines. The average age of participants was 31.1 years. They collected data through questionnaires and hospital records. Patients with both conditions were not included. The study measured health-related quality of life (HRQoL) using the SF-36 scale. It also assessed psychological distress using the Hospital Anxiety and Depression Scale. Researchers found that both FND and migraine significantly impact HRQoL. They used multivariable linear regression to understand the relationship between the diagnosis and quality of life. The results showed that both conditions lead to substantial impairments, but there is limited comparative data. This study highlights the need for more research to better understand the differences and similarities between these two conditions and their effects on patients' lives. Clinical relevance: This research indicates that both FND and migraine significantly impair patients' quality of life, highlighting the need for effective treatment strategies.

Key Learning Points

  • Functional neurological disorder and migraine both significantly reduce quality of life for patients.
  • Patients with either condition experience notable psychological distress.
  • The study emphasizes the importance of effective treatment strategies for both FND and migraine.
  • There is a need for more research to explore the similarities and differences between FND and migraine.
  • Understanding the impact of these conditions can help improve patient care and support.

Original research

Read the original publication and review its full methods and findings on PubMed.

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