Biomarkers in Migraine Diagnosis: New Research Insights

Research Summary

A recent review published in Pain Research and Management explored the potential of biochemical biomarkers in diagnosing migraine. Traditionally, migraine diagnosis relies on clinical criteria from the International Headache Society's 2018 guidelines. This review evaluated 31 studies focusing on biochemical markers like calcitonin gene-related peptide (CGRP), pituitary adenylate cyclase-activating peptide (PACAP), and others such as cytokines and mitochondrial metabolism markers. While CGRP and PACAP show promise as diagnostic biomarkers, no specific substance has yet been identified as a practical diagnostic tool. The review highlights the need for standardized methodologies and suggests that future research could benefit from panels of easily obtainable biomarkers from blood, saliva, and urine.

Study Details

📄 Title: A Review of the Biochemical Diagnostic Biomarkers in Migraine: New Perspectives in Diagnostics.

👥 Research Team: Różycka K et al.

📚 Published In: Pain Res Manag

📅 Publication Date: 2025

⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.