Cannabinoids May Ease Migraine Symptoms: New Study Insights

Research Summary

A recent study published in Cephalalgia explores the potential of cannabinoids in treating migraine symptoms in mice. Researchers administered a combination of cannabidiol (CBD) and tetrahydrocannabinol (THC) at a 100:1 ratio to investigate its effects on symptoms induced by central calcitonin gene-related peptide (CGRP), a known migraine trigger. The study found that this cannabinoid combination effectively reduced light aversion and partially alleviated pain associated with CGRP-induced migraines. Through behavioral assays, including light/dark and automated squint assessments, the research demonstrated that CBD and THC could mitigate some migraine-related symptoms, offering insights into possible new treatments for migraine management.

Study Details

📄 Title: Cannabinoids rescue migraine symptoms caused by central CGRP administration in mice.

👥 Research Team: Zorrilla E et al.

📚 Published In: Cephalalgia

📅 Publication Date: 2025 Nov

⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.