Cortical Spreading Depression: Key Model for Migraine Aura?
- MigraineMind
- Dec 4, 2025
- 1 min read
Research Summary
A new article in the Journal of Headache and Pain explores the potential of cortical spreading depression (SD) as a model for migraine with aura. This disorder, characterized by visual disturbances and severe headaches, often involves SD, a wave of neural and glial depolarization, as a key event triggering these symptoms. While some debate exists, the article presents substantial evidence supporting SD as a valid model for understanding and treating migraines with aura. The findings highlight SD's ability to trigger trigeminal pain and its potential as a target for therapeutic intervention, suggesting its reliability in modeling migraine with aura.
Study Details
👥 Research Team: Oncel MM, Harriott AM
📚 Published In: J Headache Pain
📅 Publication Date: 2025 Dec 3
⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.