CXCL10's Role in Vestibular Migraine Explored
- MigraineMind
- Nov 19, 2025
- 1 min read
Research Summary
A recent study published in CNS Neuroscience & Therapeutics explores the role of the chemokine CXCL10 in vestibular migraine (VM) through the PI3K/AKT signaling pathway. Researchers found that serum CXCL10 levels were significantly elevated in VM patients, correlating with the severity of dizziness and headaches. In a rat model of VM, increased expression of CXCL10 and its receptor CXCR3 was observed in key brain regions. The study also noted elevated activity in the PI3K/AKT signaling pathway and related inflammatory factors, such as interleukin-1β, interleukin-6, and tumor necrosis factor-α, suggesting CXCL10's involvement in VM pathogenesis.
Study Details
👥 Research Team: Song MM et al.
📚 Published In: CNS Neurosci Ther
📅 Publication Date: 2025 Nov
⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.