Flunarizine Formulations: Effective Migraine Relief Confirmed

Research Summary

A recent study published in the journal Drugs in Research and Development compared two formulations of flunarizine hydrochloride, a key drug for migraine prevention and vertigo management, to determine their bioequivalence. Conducted on healthy Chinese subjects, the research assessed the pharmacokinetics and safety of these formulations under fasting and fed conditions. The results showed that the test formulation is bioequivalent to the marketed version, with similar absorption and effectiveness, regardless of meal conditions. Notably, a high-fat meal delayed peak drug concentration but increased exposure. Both formulations were well tolerated, with no serious side effects, affirming their clinical reliability for migraine sufferers.

Study Details

📄 Title: Bioequivalence Study of Two Formulations of Flunarizine Hydrochloride Capsules in Healthy Chinese Subjects Under Fasting and Fed Conditions.

👥 Research Team: Yang Y et al.

📚 Published In: Drugs R D

📅 Publication Date: 2025 Aug 22

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⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.