Flunarizine Formulations Proven Equal for Migraine Relief

Research Summary

A recent study published in the journal Drugs in Research and Development explored the bioequivalence of two formulations of flunarizine hydrochloride capsules, a medication crucial for preventing migraines and managing vertigo. Conducted with healthy Chinese participants, the study involved comparing the test and reference formulations under both fasting and fed conditions. The findings revealed that both formulations are bioequivalent, meaning they work the same in the body, with similar absorption and effect. Notably, consuming a high-fat meal delayed the drug's peak concentration and increased its exposure. Importantly, both formulations were well tolerated with no serious side effects, reinforcing their safety and effectiveness for migraine prophylaxis.

Study Details

📄 Title: Bioequivalence Study of Two Formulations of Flunarizine Hydrochloride Capsules in Healthy Chinese Subjects Under Fasting and Fed Conditions.

👥 Research Team: Yang Y et al.

📚 Published In: Drugs R D

📅 Publication Date: 2025 Aug 22

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⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.