Ketamine Infusions: Boosting Cognitive Function in Chronic Migraine?

Research Summary

A study published in CNS Drugs explored the impact of ketamine infusions on cognitive function in patients with refractory chronic migraine. The prospective, observational study involved 23 adults receiving 5-day ketamine infusions. Researchers used the telephone Montreal Cognitive Assessment to measure cognitive changes, finding a significant improvement at 1 month, but not at 6 or 12 months. Monthly migraine days declined from 27 to 22 over one year. While the study suggests no significant cognitive impairment from ketamine, its small sample size and lack of a control group limit definitive conclusions. Larger studies are needed to confirm ketamine's safety in migraine treatment.

Study Details

📄 Title: Assessing Cognitive Function over Time in Patients with Refractory Chronic Migraine Who Received Ketamine Infusions: A Prospective, Observational Study.

👥 Research Team: Vinokur M et al.

📚 Published In: CNS Drugs

📅 Publication Date: 2025 Dec 15

⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.