Migraine Insights: Shared Inflammation & Unique Pathways Found

Research Summary

A recent study published in European Journal of Medical Research explores the similarities and differences between vestibular migraine (VM) and migraine only (MO) by integrating clinical data with transcriptome sequencing. The research included 9 VM cases, 6 MO cases, and 14 healthy controls, revealing that both VM and MO share common symptoms like anxiety and sleep disorders but differ in headache frequency and vestibular dysfunction. Transcriptomic analysis highlighted IL-17 signaling as more active in VM, explaining its higher attack frequency. C-X-C motif chemokine ligand 8 (CXCL8) was identified as a shared biomarker. Potential therapies include NSAIDs, vitamin A, and verapamil.

Study Details

📄 Title: Vestibular migraine vs. migraine only: integrated transcriptome-clinical profiling reveals shared inflammation and divergent metabolic pathways for targeted therapy.

👥 Research Team: An N et al.

📚 Published In: Eur J Med Res

📅 Publication Date: 2025 Dec 11

⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.