Migraine Without Aura: Brain Network and Neurotransmitter Insights
- MigraineMind
- Nov 27, 2025
- 1 min read
Research Summary
A recent study published in Brain Research Bulletin investigates the brain network disruptions and neurotransmitter imbalances in patients with migraine without aura (MWoA) using resting-state fMRI. The study compared 53 MWoA patients to 51 healthy controls, focusing on functional integration and effective connectivity (EC) in the brain. Results showed MWoA patients had reduced functional integration in the left putamen and increased in the left angular gyrus. EC changes between subcortical and cortical regions correlated with headache frequency and disease duration. Additionally, disrupted brain patterns overlapped with serotonin, dopamine, and glutamate pathways, associated with quality-of-life impairments.
Study Details
👥 Research Team: Zhang Z et al.
📚 Published In: Brain Res Bull
📅 Publication Date: 2025 Nov 24
⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.