Neurovascular Clues: Chronic Migraine Linked to Precuneus Changes
- MigraineMind
- Nov 13, 2025
- 1 min read
Research Summary
Researchers found that abnormal neurovascular coupling (NVC) in the precuneus is linked to migraine chronification. Using arterial spin labeling and resting-state functional MRI, scientists assessed NVC in 39 episodic migraine (EM) patients, 61 chronic migraine (CM) patients (including 25 with medication overuse headache), and 42 healthy controls. The results showed a significant reduction in whole-brain NVC in migraine patients compared to healthy controls. CM patients had a lower CBF/ReHo ratio in the right precuneus than EM patients. Depression mediated the relationship between abnormal NVC and clinical characteristics in CM patients, suggesting NVC metrics could help diagnose migraine chronification.
Study Details
👥 Research Team: Lin C et al.
📚 Published In: Cephalalgia
📅 Publication Date: 2025 Nov
⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.