New Migraine Relief: 4 Existing Drugs Show Promising Results

Research Summary

A recent study published in Front Big Data demonstrates a promising method for identifying new migraine treatments by integrating genetic research with real-world data. Researchers leveraged genome-wide association studies to pinpoint gene expression profiles linked to migraines. These profiles were matched with drug data to find 18 existing medications that could potentially counteract migraine-related genetic changes. The study highlighted four drugs—metformin, statins, thiazolidines, and angiotensin receptor neprilysin inhibitors—with significant potential to reduce migraine attacks, showing relative risk reductions of 19%, 6%, 16%, and 31%, respectively. This innovative approach offers a cost-effective strategy for drug repositioning in migraine therapy.

Study Details

📄 Title: Integrated analysis for drug repositioning in migraine using genetic evidence and claims database.

👥 Research Team: Inokuchi S, Tajima T

📚 Published In: Front Big Data

📅 Publication Date: 2025

⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.