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New Migraine Treatments: Promising Protein Targets Identified

  • Writer: MigraineMind
    MigraineMind
  • Nov 26, 2025
  • 1 min read

Research Summary


In an exciting study published in Molecular Neurobiology, researchers have identified potential drug targets for migraine using Mendelian randomization and plasma proteome data. By analyzing data from Decode, UKB-PPP, and Interval databases, they identified 11 proteins potentially linked to migraine, narrowing down to 8 significant proteins through further analysis. Among these, CALCB and TBC1D17 stood out, with CALCB linked to increased migraine risk and TBC1D17 to reduced risk. CALCB is already being explored as a migraine treatment, highlighting TBC1D17's potential. This research sets the stage for future studies to confirm these findings and explore TBC1D17’s role in migraine management.


Study Details

 

👥 Research Team: Guo L et al.

📚 Published In: Mol Neurobiol

📅 Publication Date: 2025 Nov 25

 

⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.

 
 

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