New Polysaccharide in TCM Shows Promise for Migraine Relief

Research Summary

A recent study published in Carbohydrate Polymers delves into the structural and pharmacokinetic properties of Tianshu Capsule (TSC), a traditional Chinese medicine known for its migraine-relieving effects. Researchers identified two polysaccharides: a 1,4-glucan (TSCP-1a) and a novel pectin-like polysaccharide (TSCP-4) from TSC. TSCP-4 showed significant migraine symptom relief in a nitroglycerin-induced animal model. For tracking, TSCP-4 was labeled with fluorescent markers, demonstrating absorption in the small intestine and distribution to the liver and kidney. Pharmacokinetic analysis revealed favorable absorption and prolonged mean residence time, highlighting the potential of these compounds in TCM formulations for migraine treatment.

Study Details

📄 Title: Structural elucidation, in vivo tracking and pharmacokinetic profiling of a novel polysaccharide with anti-migraine efficacy.

👥 Research Team: Liu L et al.

📚 Published In: Carbohydr Polym

📅 Publication Date: 2026 Jan 15

⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.