Novel Anti-Migraine Polysaccharide Shows Promising Results

Research Summary

A recent study in Carbohydrate Polymers explores the anti-migraine potential of Tianshu Capsule (TSC), a traditional Chinese medicine. Researchers identified two key polysaccharides: 1,4-glucan (TSCP-1a) and a novel pectin-like polysaccharide (TSCP-4). In migraine-induced animal models, TSCP-4 showed significant symptom relief, aligning with the known efficacy of TSC. Using fluorescent labeling, TSCP-4 was tracked, revealing absorption in the small intestine and distribution to the liver and kidney. Pharmacokinetic profiling of F-TSCP4 indicated favorable absorption and prolonged presence in the body. This study advances our understanding of TSC's active compounds and their potential in treating migraines.

Study Details

📄 Title: Structural elucidation, in vivo tracking and pharmacokinetic profiling of a novel polysaccharide with anti-migraine efficacy.

👥 Research Team: Liu L et al.

📚 Published In: Carbohydr Polym

📅 Publication Date: 2026 Jan 15

⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.