Partial Rebreathing Fails to Relieve Migraine Aura Symptoms

Research Summary

A recent study published in the journal Headache investigated the effectiveness of a partial rebreathing device for treating migraines with aura. Conducted across 15 sites in the US and Germany, the trial enrolled 142 participants aged 18-65. The study aimed to determine if carbon dioxide-enriched gas could help alleviate symptoms when used early in the aura stage. However, the trial was terminated early due to a lack of effectiveness. Key results showed no significant difference in pain reduction between the sham and active groups at 2 hours post-treatment. This suggests that partial rebreathing is not effective for migraines with aura.

Study Details

📄 Title: Partial rebreathing is not effective for early treatment of migraine with aura attacks: Results of a double-blind, randomized, controlled trial (PAREMA1).

👥 Research Team: Gaul C, Ferreira S, Johansen T

📚 Published In: Headache

📅 Publication Date: 2025 Nov 21

⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.