Standardizing "Migraine Day" for Better Treatment Consistency

Research Summary

A recent study published in the journal Cephalalgia highlights significant variation in the definition of a "migraine day" across 23 phase III trials involving drugs targeting the calcitonin gene-related peptide (CGRP) pathway for migraine prevention. The research uncovered 12 different definitions, with discrepancies in headache duration, the inclusion of probable migraine, and whether treated migraines were considered. Notably, only two trials included headaches lasting less than 30 minutes. The study underscores the urgent need for a standardized definition of a migraine day to enhance both clinical practice and research consistency in migraine treatment trials.

Study Details

📄 Title: What's a migraine day? Analysis of the variety in the definition of a migraine day across phase III trials with drugs targeting the CGRP pathway.

👥 Research Team: Loose L et al.

📚 Published In: Cephalalgia

📅 Publication Date: 2025 Nov

⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.