The Power of Positive Words: Placebo Effects in Migraines

Research Summary

A recent study published in Psychotherapy and Psychosomatics explored how verbal instructions can influence the placebo effect in migraine patients. The researchers conducted a randomized controlled trial with 102 outpatients, dividing them into two groups. One group received a pharmacological prescription accompanied by strongly positive verbal instructions, while the other received the prescription with merely positive instructions. Patients were assessed over several months using the Headache Impact Test and Numeric Rating Scales. Findings revealed that strongly positive instructions did not reduce headache impact significantly, while positive instructions did. The study concluded that strongly positive verbal instructions did not trigger a placebo effect.

Study Details

📄 Title: Placebo effect of verbal instructions coupled with pharmacological treatment: results from a randomized controlled trial in migraine patients.

👥 Research Team: Romanazzo S et al.

📚 Published In: Psychother Psychosom

📅 Publication Date: 2025 Nov 18

⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.