Ubrogepant vs. Triptans: New Hope for Migraine Relief

Research Summary

A recent study published in the journal Pain Management explored the real-world effects of switching migraine treatments from one oral triptan to another or to ubrogepant. The study involved 211 participants who used the Migraine Buddy app and had switched treatments. Results showed that those who switched to ubrogepant reported higher satisfaction in managing migraine pain and annoying symptoms compared to those who switched to another triptan. Specifically, 69.4% of the ubrogepant group were satisfied, versus 42.0% in the triptan group. Additionally, more ubrogepant users preferred their new medication and experienced meaningful relief within two hours of treatment.

Study Details

📄 Title: Patient-centered outcomes in the acute treatment of migraine: a prospective, real-world, longitudinal survey study (UNIVERSE II) comparing migraine patients who switch from a prior triptan to another triptan or ubrogepant.

👥 Research Team: Lipton RB et al.

📚 Published In: Pain Manag

📅 Publication Date: 2025 Nov 19

⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.