Understanding Placebo Effects in Migraine Treatments: Key Insights
- MigraineMind
- 3 days ago
- 1 min read
Research Summary
Researchers identified placebo responses in migraine treatment through a systematic review and meta-analysis of 126 randomized controlled trials from 1988 to 2024, involving 25,542 placebo recipients. In adults experiencing acute migraines, 13% achieved "Pain Free" status, while 35% experienced "Pain Relief". Prophylactic trials showed a reduction of -2.83 monthly migraine days and -3.64 monthly headache days, with a 28% "≥50% responder rate for monthly migraine days". Children's placebo responses were nearly double those in adults. Key influences on placebo responses included endpoint definition, migraine subtype, and administration route. Many older trials failed to meet current reporting standards, potentially skewing results.
Study Details
👥 Research Team: Bruijn NRA et al.
📚 Published In: Neurol Clin
📅 Publication Date: 2026 Feb
⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.