Understanding SMART Syndrome: A Post-Radiation Migraine Challenge

Research Summary

A recent paper in Cureus highlights the complexities of diagnosing Stroke-Like Migraine Attacks After Radiation Therapy (SMART) syndrome, a rare complication occurring years after cranial radiotherapy. This condition presents with symptoms like headaches, hemiparesis, aphasia, seizures, and confusion. The case study involves a 64-year-old man who experienced abnormal movements years post-radiation, leading to a diagnosis of SMART syndrome. While initial tests were normal, MRI showed cortical changes, and EEG indicated seizures. Treatment involved optimizing antiepileptic therapy, resulting in improved consciousness and reduced seizures. This case underscores the need for awareness of SMART syndrome in patients with a history of cranial irradiation.

Study Details

📄 Title: Stroke-Like Migraine Attacks After Radiation Therapy (SMART) Syndrome: A Diagnostic Challenge a Decade After Cranial Irradiation.

👥 Research Team: Aggarawal AK, Mon NSY, Gazi M

📚 Published In: Cureus

📅 Publication Date: 2025 Dec

⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.