Unlocking Migraine Mysteries: New Genetic Insights Revealed
- MigraineMind
- Nov 30, 2025
- 1 min read
Research Summary
A groundbreaking study published in The Journal of Headache and Pain sheds light on the genetic underpinnings of migraines. Researchers explored the role of DNA methylation, an epigenetic modification, in migraine risk using data from brain and blood samples. They identified 169 CpG sites affecting migraine risk, linking them to 68 genes, with further subtype analysis expanding this to 72 genes. Among these, 12 high-confidence genes, including CFDP1, ICA1L, and SERPING1, were highlighted for their significant potential in understanding and treating migraines. Additionally, drug-gene interaction analyses suggest therapeutic targets like MAPT and CALCA, offering new insights into migraine pathophysiology.
Study Details
👥 Research Team: Liu M et al.
📚 Published In: J Headache Pain
📅 Publication Date: 2025 Nov 28
⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.