Unlocking Migraine Relief: Tianshu Capsule's Polysaccharides Explained

Research Summary

Researchers have made strides in understanding how Tianshu Capsule (TSC), a traditional Chinese medicine, alleviates migraines. This study, published in Carbohydrate Polymers, focuses on the structural and pharmacokinetic profiling of TSC's polysaccharides. Two key components, a 1,4-glucan (TSCP-1a) and a novel pectin-like polysaccharide (TSCP-4), were identified. In a migraine model, TSCP-4 significantly reduced symptoms, echoing TSC's therapeutic effects. Tracking the polysaccharide in vivo revealed its absorption in the small intestine and distribution to the liver and kidney. The findings illuminate the oral absorption and bioactivity of TSC, offering insights into the foundation of compound polysaccharides in traditional medicine.

Study Details

📄 Title: Structural elucidation, in vivo tracking and pharmacokinetic profiling of a novel polysaccharide with anti-migraine efficacy.

👥 Research Team: Liu L et al.

📚 Published In: Carbohydr Polym

📅 Publication Date: 2026 Jan 15

⚕️ Medical Disclaimer: This summary is generated automatically from recent migraine research. Always consult with healthcare professionals for medical advice.