Efficacy of prefrontal-occipital transcranial direct current stimulation for refractory chronic migraine.

Patients with chronic migraine often do not respond to standard medical treatments. This resistance likely comes from the complex nature of their pain. Transcranial direct current stimulation, or tDCS, is a new non-invasive therapy. This study analyzed the effectiveness of tDCS for treating chronic migraine patients. Thirty patients received tDCS treatment targeting specific brain regions for a total of eight weeks. The treatment sessions included three days each week for two weeks, then weekly sessions for six weeks. Results showed significant pain reduction for all participants, regardless of medication-overuse headache status. Eighty% of patients experienced over 50% reduction in headache duration. Additionally, 70% had more than 50% decrease in severe headache days. Participants reported good tolerability with no serious side effects. Overall, tDCS appears promising for chronic migraine sufferers resistant to usual therapies, potentially improving their quality of life significantly. Clinical relevance: This study suggests tDCS may provide effective relief for chronic migraine patients.