MigraineMind research summary
Long-term efficacy and predictors of response to greater occipital nerve pulsed radiofrequency in migraine with prior preventive treatment failure.
Acta Neurol Belg | 2026
Observational studySummary
In this study, researchers looked at a treatment for migraines called Greater Occipital Nerve (GON) Pulsed Radiofrequency (PRF). This treatment is for patients who haven't had success with other preventive treatments. The study involved 116 adults with migraines and treatment failures. Researchers wanted to see how effective this treatment was after one year. They measured success by checking if patients reached a state called Patient Acceptable Symptom State (PASS). They also tracked changes in monthly headache days and patients' overall improvement. After 12 months, 70 out of 116 patients reported significant improvement. The researchers also looked for factors that predicted which patients would respond best to the treatment. Overall, this study suggests that GON PRF can be a helpful option for patients struggling with migraines after other treatments failed. Clinical relevance: This study indicates that GON PRF may provide lasting relief for migraine patients who have not responded to previous treatments.
Key Learning Points
- GON Pulsed Radiofrequency treatment is a potential option for migraine patients who have not found relief with other preventive treatments.
- After one year, 70 out of 116 patients experienced significant improvement in their migraine symptoms.
- The treatment's effectiveness was measured by patients reaching a state of acceptable symptom relief, known as PASS.
- Tracking monthly headache days showed a notable reduction in frequency for many patients receiving GON PRF.
- Identifying factors that predict treatment response can help tailor migraine management for individual patients.
Research Informatics
RETROSPECTIVE COHORT STUDY
GON PRF shows long-term benefits in migraine treatment failure cases.
conditionMigraine with prior preventive treatment failure
sample Size116
populationAdults with migraine and prior preventive treatment failure
study DesignRetrospective cohort
exposureGreater Occipital Nerve Pulsed Radiofrequency
study PeriodOne year
Related migraine research topics
Original research
Read the original publication and review its full methods and findings on PubMed.
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