Migraine Prevention Research
Explore migraine prevention research, including preventive treatments, clinical trials, Botox and treatment strategies.
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Guanfacine as a potential preventive therapy for chronic migraine: a mechanistic hypothesis.
Authors: Kesayan T, Patel K Clinical trial
Guanfacine is a medication that may help prevent chronic migraines. Many patients still struggle with migraines despite existing treatments. About one-third of chronic migraine patients do not find relief. Current…
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Persistence and Reasons for Treatment Discontinuation of Anti-CGRP Therapies in Migraine Prophylaxis: A Systematic Review and Meta-analysis of Real-World Studies.
Authors: Pellesi L, Yangjeh A, Hajjaj I, Onan D, Waliszewska-Prosół M Systematic review / meta-analysis
Anti-CGRP therapies are important for preventing migraines. This study looked at how long patients stay on these treatments. It also examined why some patients stop using them. Researchers gathered data from various…
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Therapeutic Applications of rTMS in Migraine Prophylaxis.
Authors: Siokas V, Marogianni C, Liampas I, Sokratous M, Tsirelis D Review
Migraine is a significant cause of disability, especially for young adults. Many patients benefit from recent preventive therapies, but some still struggle with treatment. Repetitive Transcranial Magnetic Stimulation…
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OnabotulinumtoxinA Improves Sleep Quality in Patients with Chronic Migraine: A Prospective Real-World Study.
Authors: Viticchi G, Falsetti L, Bartolini M, Salvemini S, De Vanna G Observational study
months of treatment. Researchers found that sleep quality improved significantly in patients after receiving OBT-A. Specifically, 63% of patients reported better sleep after three months. Patients also experienced…
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Early improvements in function with atogepant as assessed by the Activity Impairment in Migraine-Diary: Post hoc analyses of three randomized, phase 3 clinical trials of atogepant for the preventive treatment of migraine.
Authors: Lipton RB, Gandhi P, Gantenbein AR, Dabruzzo B, Carr K Clinical trial
Atogepant is a new treatment for preventing migraines. This study looked at how it helps improve daily activities. Researchers analyzed data from three large clinical trials. They focused on patient-reported outcomes…
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Comparative Efficacy of Acupuncture, Pharmacological Interventions, Sham Acupuncture, and Placebo for Migraine Prevention: A Bayesian Network Meta-Analysis.
Authors: Zhu Q, Wang Y, Yang X, Yang J, Song X Systematic review / meta-analysis
This study looked at how well acupuncture, medications, sham acupuncture, and placebo work for preventing migraines. Researchers reviewed 32 randomized controlled trials to gather data. They focused on how these…
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Depressive and anxiety symptoms during CGRP-targeted migraine prevention: A systematic review and meta-analysis.
Authors: Al-Sayegh Z, Al-Khazali S, Al-Khazali HM, Christensen RH, Videbech P Systematic review / meta-analysis
Migraine often occurs alongside depression and anxiety, worsening patients' overall health. This study looked at how CGRP-targeted therapies affect these mental health symptoms. CGRP-targeted treatments are effective…
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Effectiveness of Rimegepant for the Acute Treatment of Migraine Among Participants Using Different Types of Preventive Therapy: Analyses from CONFIDENCE.
Authors: Lipton RB, Goadsby PJ, Pozo-Rosich P, Urani A, Lambru G Observational study
This study looked at how well rimegepant works for treating migraines. Researchers focused on patients using different preventive medications. The study involved participants in the United States who had 3-14…
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Candesartan for Migraine Prophylaxis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Authors: Abdeldayem MR, Elsherbeeny A Systematic review / meta-analysis
This study reviewed the effectiveness of candesartan for preventing migraines. Migraines are common and can severely impact daily life. Many patients struggle with current preventive treatments due to side effects or…
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Retrospective Review of Dual CGRP-Targeted Regimens for Acute and Preventive Treatment of Migraines in a Veteran Population.
Authors: Forrest A, Billow D, Martin A Clinical trial
A recent study examined the safety and effectiveness of dual CGRP-targeted treatments for migraines. Researchers focused on patients who used both preventive and acute CGRP medications. The study included 89…
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Nutritional supplements for migraine prevention: evaluating evidence sufficiency and effect modifiers through network meta-analysis, trial sequential analysis, and meta-regression.
Authors: Peng J, Zhou L, Chen Y, Li J, Zhang R Systematic review / meta-analysis
This research looked at how well nutritional supplements can prevent migraines. The study used advanced methods to compare different supplements based on their effectiveness and safety. Researchers gathered data from…
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Pharmacologic Treatment for Migraine Prevention in Adults Practice Guideline Recommendations: Report of the AAN Guidelines Subcommittee and the American Headache Society.
Authors: Potrebic S, Tanveer S, Becker WJ, Burch R, Cooke LJ Guideline / consensus
This research paper offers updated guidelines for preventing migraines in adults. A group of experts reviewed recent studies and evidence. They aimed to create clear recommendations for healthcare providers. The…
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Systematic Review of Pharmacologic Treatment for Migraine Prevention in Adults: Report of the AAN Guidelines Subcommittee and the American Headache Society.
Authors: Pringsheim T, Smith DB, Tanveer S, Becker WJ, Burch R Guideline / consensus
This systematic review examines the effectiveness of medications for preventing migraines in adults. It aims to provide updated guidelines for clinicians treating migraine patients. A multidisciplinary team reviewed…
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Pharmacologic Treatment for Migraine Prevention in Adults Practice Guideline Recommendations: Report of the AAN Guidelines Subcommittee and the American Headache Society.
Authors: Potrebic S, Tanveer S, Becker WJ, Burch R, Cooke LJ Guideline / consensus
This research paper updates guidelines for preventing migraines in adults. A panel of experts reviewed recent studies to create these recommendations. They focused on when to start preventive medications for…
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Systematic Review of Pharmacologic Treatment for Migraine Prevention in Adults: Report of the AAN Guidelines Subcommittee and the American Headache Society.
Authors: Pringsheim T, Smith DB, Tanveer S, Becker WJ, Burch R Guideline / consensus
This systematic review examined medications that prevent migraines in adults. It aimed to update guidelines for treating migraine based on recent evidence. A panel of experts reviewed numerous studies on migraine…
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Pharmacotherapy for chronic migraine prevention: a narrative review.
Authors: Baek Y, Yuan H, Silberstein S Review
Chronic migraine (CM) is a serious condition affecting 1-2% of people. It causes significant pain and can disrupt daily life. This research reviews various treatments for preventing CM. The authors examined studies…
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OnabotulinumtoxinA for chronic migraine: A real-life multicenter study of 479 patients.
Authors: Waliszewska-Prosół M, Marschollek K, Paczkowska M, Sławek J, Bott-Karoń M Observational study
Chronic migraine (CM) is a tough condition to treat, especially with medication-overuse headache (MOH). This study looked at how well onabotulinumtoxin A (BoNT-A) works for CM. Researchers studied 479 Polish patients…
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Deprescribing and Anti-CGRP preventive therapy in medication-overuse headache associated with migraine: pathophysiological rationale and single-center real world evidence.
Authors: Sošić M, Rački V, Fajkić A, Jašić M, Belančić A Observational study
Medication-overuse headache (MOH) is a common issue for many migraine sufferers. It happens when people take too much medication for migraines, leading to more headaches. This study looked at a new approach to…
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The Safety of OnabotulinumtoxinA (OnabotA) During Pregnancy and Breastfeeding: Implications for Chronic Migraines.
Authors: Eladawi S, Koonalintip P, Ngomuo A, Leech E, Thaller M Systematic review / meta-analysis
OnabotulinumtoxinA (OnabotA) is a treatment for chronic migraines. Migraines often affect women during pregnancy and breastfeeding. However, treatment options are limited for these women. This study looked at the…
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Lomerizine Prophylaxis for Pediatric Migraine: Efficacy and Predictors of Treatment Response-A Retrospective Cohort Study.
Authors: Shimomura H, Tokunaga S, Taniguchi N, Terasaki E, Yoshitake S Observational study
Lomerizine is a medication used to prevent migraines, particularly in children. This study looked at 83 patients aged 18 and younger who received lomerizine. Researchers wanted to see how effective it was in reducing…