Systematic Review of Pharmacologic Treatment for Migraine Prevention in Adults: Report of the AAN Guidelines Subcommittee and the American Headache Society.

This systematic review examines the effectiveness of medications for preventing migraines in adults. It aims to provide updated guidelines for clinicians treating migraine patients. A multidisciplinary team reviewed studies from various databases, including MEDLINE and Embase. They focused on randomized controlled trials that tested preventive treatments for episodic and chronic migraines. The review included studies up to June 6, 2024. Researchers evaluated outcomes like the number of headache days and patient-reported quality of life. They calculated different statistical measures to assess treatment effectiveness. The findings will help shape new practice guidelines for healthcare providers. This research is important for understanding how to manage migraines better. It highlights the need for effective preventive strategies to improve patients’ lives. Overall, this review contributes valuable information to enhance migraine treatment options for adults suffering from this debilitating condition. Clinical relevance: This research provides updated guidelines for clinicians, improving migraine prevention strategies for patients.