Therapeutic Applications of rTMS in Migraine Prophylaxis.

Migraine is a significant cause of disability, especially for young adults. Many patients benefit from recent preventive therapies, but some still struggle with treatment. Repetitive Transcranial Magnetic Stimulation (rTMS) is a new option for these patients. Researchers reviewed literature to find how effective rTMS is for migraines. They searched PubMed and Scopus for studies published until March 2026. A total of 24 articles were included in their review. These articles focused on various brain areas, like the primary motor cortex and the dorsolateral prefrontal cortex. High-frequency rTMS (HF-rTMS) showed promise in reducing migraine days and pain intensity. This suggests that rTMS could be a valuable therapy for patients who do not respond to traditional medications. Overall, rTMS may offer hope for those struggling with chronic migraines and looking for new treatment options. Clinical relevance: This research indicates that rTMS could provide effective migraine prevention for patients unresponsive to standard treatments.