Migraine Prevention Research

Explore migraine prevention research, including preventive treatments, clinical trials, Botox and treatment strategies.

1. Suppression of cortical spreading depression in migraine prophylaxis

   Annals of Neurology | 2006

   Authors: Ayata et al. Review

   Topiramate, valproate, propranolol, amitriptyline, and methysergide are commonly used for migraine prevention. However, their exact action mechanisms remain uncertain. Cortical spreading depression (CSD) is linked to…

   MigraineMind Top 100 · #86
2. Topiramate for Migraine Prevention<SUBTITLE>A Randomized Controlled Trial</SUBTITLE>

   JAMA | 2004

   Authors: Brandes Clinical trial

   Topiramate is an antiepileptic drug that may help prevent migraines. A large study tested topiramate's efficacy and safety in preventing migraines. The study included 483 patients aged 12 to 65 years. These patients…

   MigraineMind Top 100 · #76
3. Botulinum Toxin Type A as a Migraine Preventive Treatment

   Headache The Journal of Head and Face Pain | 2000

   Authors: Silberstein et al. Clinical trial

   Botulinum toxin type A, known as BOTOX, is assessed for migraine prevention. Current treatments often fail due to low effectiveness or adverse effects. BOTOX injections help relieve pain from conditions like cervical…

   MigraineMind Top 100 · #98
4. Flunarizine in Prophylaxis of Childhood Migraine: A Double-Blind, Placebo-Controlled, Crossover Study

   Cephalalgia | 1988

   Authors: Sorge et al. Clinical trial

   A recent study investigated flunarizine's effectiveness in preventing childhood migraines. Seventy children participated in this 8-month double-blind, placebo-controlled, crossover trial. After four weeks without…

   MigraineMind Top 100 · #4