Latest Migraine & Headache Research
MigraineMind provides concise summaries, key learning points and links to the original scientific publications behind recently published migraine and headache research. Learn about MigraineMind or read how the research summaries are made.
Browse migraine research by topic
Explore focused collections that currently meet MigraineMind’s five-paper quality threshold.
-
Ligustrazine Alleviates Nitroglycerin-Induced Migraine by Regulating Mitochondrial Energy Metabolism Through the Concurrent Regulation of CypD, ANT, and PAR2.
Ligustrazine (Lig) is a compound that may help reduce migraine symptoms. Researchers studied its effects on migraines caused by nitroglycerin (NTG) in rats. They also tested it on nerve cells called PC12. The study…
-
Greater occipital nerve block versus intranasal sphenopalatine ganglion block in chronic migraine with failure of at least two oral preventive treatments: a prospective, non-randomised patient-preference comparative study.
This study compared two treatments for chronic migraine: greater occipital nerve (GON) block and intranasal sphenopalatine ganglion (SPG) block. Both treatments were given to patients who failed at least two oral…
-
Effects of Acupuncture on Cerebral Blood Flow in Episodic Migraine Patients Investigated by Arterial Spin Labeling MRI.
women) and eleven healthy controls participated in the study. The results showed that acupuncture significantly increased cerebral blood flow in migraine patients. This increase was observed during and after…
-
Efficacy and exploratory treatment-response modeling of acupuncture for acute migraine based on DIA proteomics: a study protocol for a randomized controlled trial.
r acute migraine and explore treatment-response modeling using proteomics. The research will involve a randomized controlled trial design. Participants will receive acupuncture to assess its impact on migraine…
-
Cost-utility analysis of erenumab preventive treatment for chronic migraine in China.
This study looked at the cost-effectiveness of erenumab for chronic migraine in China. Erenumab is a preventive treatment given as an injection every four weeks. Researchers compared its effects to no preventive…
-
Diet quality in pediatric migraine and the educational quality of related short-form videos: a cross-sectional study and content analysis.
This study looked at diet quality and short-form videos about migraine in children. Researchers included 180 children, aged 7 to 18 years, who suffer from migraines. They assessed diet quality using a specific…
-
Hypothalamic subregional volume in relation to VSS-C total symptom burden in women with migraine: an exploratory cross-sectional MRI study.
This research explored how the structure of the hypothalamus relates to migraine symptoms. It focused on 39 women diagnosed with migraine. Researchers used advanced MRI techniques to analyze brain images. They…
-
Supraorbital Nerve Decompression for the Treatment of Chronic Refractory Migraine: Case Report and Review of the Literature.
Chronic migraine affects millions and can severely limit daily activities. Many patients do not respond well to traditional treatments. This case study focuses on a 73-year-old man with chronic migraines. His…
-
Efficacy and Safety of Non-invasive Brain Stimulation in Non-migraine Primary Headache Disorders: A Systematic Review and Meta-analysis.
Non-migraine primary headache disorders, like tension-type and cluster headaches, are common. These headaches can be chronic and seriously affect daily life. Current treatment options often provide limited relief…
-
COMPARATIVE EFFICACY OF 200 UNITS VERSUS 155 UNITS OF ONABOTULINUMTOXIN A FOR CHRONIC MIGRAINE.
This study looked at how effective different doses of onabotulinumtoxin A (OnaBT-A) are for treating chronic migraine. Chronic migraine affects many people and can be hard to manage. Researchers conducted this study…
-
New insights into understanding Xiongzhi Qufeng Zhitong Granule's anti-migraine effects and mechanism on reserpine-induced mice: from network pharmacology, molecular dynamics simulation, and experimental validation.
Xiongzhi Qufeng Zhitong Granule (XZQF) is a traditional Chinese medicine for migraines. This study investigates how XZQF helps reduce migraine symptoms in mice. Researchers used a model where migraines were triggered…
-
Time Course of Rimegepant Effect for Acute Treatment of Migraine in Adults Unsuitable for Triptans: Exploratory Endpoints from a Phase 4, Randomized, Double-Blind, Placebo-Controlled Study.
A recent study explored the effects of rimegepant for treating migraines. This trial focused on adults who cannot use triptans. Participants received a single dose of rimegepant 75 mg or a placebo. The study measured…
-
Ultrasound-guided continuous radiofrequency of the C2 dorsal root ganglion for menstrually related migraine: a comparative clinical study.
Menstrually related migraine (MRM) affects many women and causes significant discomfort. It often comes with symptoms like nausea, anxiety, and depression. Traditional treatments, like the medication zolmitriptan…
-
Investigating the mechanism of Xiongfu formula and its active ingredient Z-Ligustilide alleviates chronic migraine by modulating the MAPK/ERK/CREB pathway and microglia-mediated neuroinflammation.
Chronic migraine is a painful condition that can disrupt daily life. Traditional Chinese medicine views it as a result of stagnated Qi and poor blood flow. The Xiongfu formula is a classic herbal remedy for…
-
Suspected acrylamide toxicosis associated with ingestion of consumer polyacrylamide-based hydrogel migraine caps, eye masks, and wraps in 45 dogs.
Researchers studied 45 dogs that showed signs of illness after ingesting products. These products included polyacrylamide-based hydrogel migraine caps, eye masks, and wraps. The study aimed to understand the effects…
-
Cortical Spreading Depression Mimicking Ischemic Stroke: A Case Report of Complex Hemiplegic Migraine with Reversible Cortical Magnetic Resonance Imaging Changes.
A 66-year-old man experienced a rare type of migraine called hemiplegic migraine. This migraine caused him to have sudden weakness on his left side and trouble speaking. His symptoms looked similar to a stroke, which…
-
Guanfacine as a potential preventive therapy for chronic migraine: a mechanistic hypothesis.
Guanfacine is a medication that may help prevent chronic migraines. Many patients still struggle with migraines despite existing treatments. About one-third of chronic migraine patients do not find relief. Current…
-
Migraine 1-2-3-4-5: a candidate communication aid for adult migraine without aura.
Migraine is a common and often overlooked condition affecting many people globally. This research introduces Migraine 1-2-3-4-5, a new communication tool for adults with migraines. It organizes key features of…
-
Omega-3 Supplementation with Lipid Biomarker Assessment in Youth with Migraine: A Quasi-Randomized Controlled Feasibility Trial.
This study explored whether omega-3 supplements could help young people with migraines. Researchers focused on children and teens aged 10 to 17 years. They conducted a trial at two pediatric neurology clinics…
-
The Migraine Care Gap: A Qualitative Analysis of Patients' Perspectives on Medical Progress and Persistent Unmet Needs.
Despite advances in migraine care, many patients feel their needs are unmet. This study looked at how patients view changes in migraine treatment over the last decade. Researchers analyzed 446 patient comments from…