Latest Migraine & Headache Research
MigraineMind provides concise summaries, key learning points and links to the original scientific publications behind recently published migraine and headache research. Learn about MigraineMind or read how the research summaries are made.
Browse migraine research by topic
Explore focused collections that currently meet MigraineMind’s five-paper quality threshold.
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Cost-Effectiveness and Cost-Utility Analysis of Cinnarizine Compared to Valproate in Pediatric Migraine: An Iranian Perspective.
Cinnarizine and Valproate are medications used to prevent migraines in children. This study compared the cost-effectiveness of these two treatments. It involved 150 children aged 5 to 17 years in Shiraz, Iran. The…
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Association between serum calcium concentrations and neuropsychological symptoms of migraine patients in early pregnancy.
Migraine affects many women during early pregnancy, leading to neuropsychological issues. This study looked at how migraine might impact mental health in pregnant women. It focused on serum calcium levels, which are…
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Cluster Analysis of Global Research Hotspots and Thematic Evolution in Chronic Migraine: A Bibliometric Study (1917-2024).
Chronic migraine is a common and debilitating neurological condition affecting many people. This study examined research trends on chronic migraine from 1917 to 2024. Researchers used cluster analysis to identify…
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Semantic Content of Visual Consequent Stimuli Modulates Audiovisual Learning in Migraine.
This study looked at how migraine affects learning from sound and visual cues. Researchers tested 30 adult migraine patients using two different learning tasks. The tasks involved associating sounds with visual…
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A woman in her 40s with an unusual migraine attack.
Migrainous infarction is a rare but serious complication of migraine with aura. It affects 0.5-1.5% of all ischaemic strokes. Women using oral contraceptives face increased stroke risks. This study describes a woman…
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Safety and Efficacy of Atogepant for Migraine Prevention: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Migraine is a common neurological disorder that can severely affect daily life. Atogepant is a new oral medication designed to prevent migraines. This study reviewed six high-quality trials involving 3,453 patients…
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Musculoskeletal impairments associated with migraine in young adults: a case-control study.
Migraine is common among university students and often linked to neck pain. Many students experience postural changes and musculoskeletal issues alongside migraines. This study looked at how core and cervical muscle…
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The diagnostic order of migraine-depression comorbidity associates with physical, mental, and social disability.
This research explored how the order of migraine and depression diagnoses affects health. Researchers analyzed data from over 327,000 people in the UK Biobank. They looked at groups with different diagnosis…
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Virtual Reality-Based Vestibular Rehabilitation for Vestibular Migraine: A Randomized Trial.
This study looked at whether virtual reality-based vestibular rehabilitation (VR-VestRehab) helps people with vestibular migraine (VM). Researchers included 40 patients aged 18 to 60 with definite VM. Participants…
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Peripheral CD4 T-Cell State Remodeling in Migraine Revealed by Single-Cell RNA Sequencing.
Migraine is a complex condition that may involve the immune system. This study looked at immune cells in migraine patients compared to healthy individuals. Researchers used advanced techniques to analyze blood…
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Suspected reversible cerebral vasoconstriction syndrome following ethinylestradiol-containing oral contraceptive use in a patient with migraine.
A transgender woman with a history of migraine experienced severe headaches and seizures. This occurred after starting an oestrogen-containing oral contraceptive for gender-affirming therapy. Oestrogen can increase…
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A status update on the unkept promise of high-frequency spinal cord stimulation for treatment-refractory chronic migraine.
Chronic migraine is a challenging condition, especially when treatments fail. High-frequency spinal cord stimulation (HF-SCS) is a new approach for these patients. This method uses a frequency of 10 kilohertz, which…
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Photophobia in migraine: Electrophysiological analysis of chromatic opponent responses via electroretinogram and visual evoked potential.
Migraine is a painful condition that often causes extreme sensitivity to light, known as photophobia. This sensitivity affects nearly 90% of migraine sufferers during attacks. Researchers aimed to understand why this…
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Fremanezumab for the preventive treatment of migraine in Chinese adults: A Phase 3, randomized controlled trial with an open-label extension.
Fremanezumab is a treatment approved for migraine prevention in many countries. This study focused on its effects in Chinese adults with migraines. Researchers conducted a Phase 3 trial with three groups. One group…
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A global comparison of clinical guidelines for the diagnosis and management of migraine: similarities, differences, and gaps.
This research paper compares clinical guidelines from various countries for diagnosing and managing migraines. It looks at recommendations from 2012 to 2025 across American, British, Italian, Japanese, French, and…
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Migraine Headaches in a Pediatric Patient With SETD5-Related Neurodevelopmental Disorder and Inflammatory Comorbidities: A Case Report.
This research discusses a rare genetic condition called SETD5-related neurodevelopmental disorder. It affects children and is linked to a mutation in the SETD5 gene. This condition can cause intellectual disability…
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<i>DNAJC12</i> p.Asp44Gly associated with mild hyperphenylalaninemia and migraine-like headaches: Structural and deep learning analyses.
A recent study explored a genetic variant in the DNAJC12 gene. This variant is linked to mild hyperphenylalaninemia and migraine-like headaches. Researchers examined a 19-year-old man with these symptoms. He also…
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Plasma metabolomic signatures of migraine in 479,760 adults.
Migraine is often linked to metabolic and vascular issues. This study looked at plasma metabolites in 479,760 adults from the UK Biobank. Researchers focused on 6,724 adults diagnosed with migraine during follow-up…
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Ultrasound assessment of cerebrovascular risk via breath-holding index in migraine patients treated with anti-CGRP monoclonal antibodies: a pilot study.
Migraine is a highly disabling condition affecting many people worldwide. New treatments using monoclonal antibodies target a specific pathway related to migraines. However, their effects on blood flow in the brain…
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Ginger for the treatment and prevention of migraine headaches: a systematic review and meta-analysis of randomised controlled trials.
Ginger has been studied as a potential treatment for migraine headaches. Researchers looked at various studies comparing ginger to placebo or standard treatments. They focused on how ginger affects headache severity…
