Latest Migraine & Headache Research
MigraineMind provides concise summaries, key learning points and links to the original scientific publications behind recently published migraine and headache research. Learn about MigraineMind or read how the research summaries are made.
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Explore focused collections that currently meet MigraineMind’s five-paper quality threshold.
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Nose-to-Brain Nanocarriers for Migraine Management: A Comprehensive Review of Drug Delivery Strategies and Translational Challenges.
Migraine is a common neurological disorder that causes severe pain. It can disrupt daily life due to intense and prolonged attacks. Current treatments, like oral medications, often have side effects or poor…
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Migraine with visual aura, unilateral mydriasis and Takotsubo Syndrome. Random coincidence or common pathogenesis? The precarious balance of the autonomic nervous system and the complex relationship between brain and heart: a review of the literature.
Recent research explored the link between migraine with visual aura and Takotsubo Syndrome. A woman experienced a migraine attack, followed by Takotsubo Syndrome days later. This prompted a review of existing studies…
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Impact of Migraine and its Management in 5 Gulf Countries: Results of Social Media Platforms Listening Study.
Migraine is a widespread neurological disorder affecting many people worldwide. It often goes undiagnosed and untreated, leading to significant suffering. This study looked at discussions about migraine on social…
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Phenotype-guided selection of venlafaxine and topiramate for vestibular migraine: a narrative review.
Vestibular migraine (VM) causes recurrent vertigo and is often underdiagnosed. It has various symptoms, making diagnosis challenging. There are no validated biomarkers for VM. Recent research suggests personalized…
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Lamotrigine prophylaxis is associated with reduced aura frequency in patients with burdensome migraine aura: a retrospective observational study.
Migraine aura affects about one-third of migraine sufferers. For some, this condition is very disabling. Effective treatments are often lacking for these patients. This study looked at lamotrigine (LTG) as a…
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Interictal cognitive event-related potentials in migraine subtypes: association with neuropsychiatric symptoms.
Migraine patients often report cognitive decline, impacting their daily lives. This study examined cognitive event-related potentials (CERP) in different migraine subtypes. Researchers analyzed 173 participants…
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Effectiveness and safety of sumatriptan 85 mg/naproxen sodium 500 mg combination for acute migraine: prospective real-world evidence from the GRASP Study Group.
This study explored how effective and safe a combination of sumatriptan and naproxen is for treating migraines. The research involved 111 patients who experienced multiple migraine attacks. Each patient received the…
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White matter lesions in migraine: a single-center retrospective study of prevalence and risk factors.
Migraine is a common and disabling neurological disorder affecting many people. This study looked at white matter lesions (WML) in migraine patients in the UAE. It included 313 patients aged 10-50 years who had brain…
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EEG microstate responses of migraine patients to transcutaneous electrical nerve stimulation.
Migraine patients show distinct patterns in their brain activity, known as EEG microstates. This study looked at how these patterns change with treatment using transcutaneous electrical nerve stimulation (TENS)…
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EEG Connectivity Signatures in Migraine and Tension-Type Headache: A Multimethod ROI-Based Functional Connectivity and Machine-Learning Analysis.
Researchers studied the brain activity of people with migraines and tension-type headaches. They wanted to find out if specific brain patterns could differentiate these headaches from healthy individuals. The study…
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Comorbidity of Temporomandibular Disorders, Anxiety, Depression, and Poor Sleep Quality in Episodic and Chronic Migraine: A Cross-Sectional Observational Study.
This study looked at the link between temporomandibular disorders (TMD) and migraine. Researchers focused on two types of migraine: episodic migraine (EM) and chronic migraine (CM). They wanted to see if TMD made…
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Greater Mediterranean Diet Adherence Is Associated with Lower Odds of Chronic Migraine: A Retrospective Observational Study.
This study explored how following a Mediterranean diet (MD) affects migraines. Researchers looked at 448 patients with migraines, both episodic and chronic. They measured MD adherence using a specific questionnaire…
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Evaluating the Risk of Ischemic Stroke With Low-Dose Combined Oral Contraceptives in Women With Migraine: A Nationwide Claims Database Study.
Combined oral contraceptives (COCs) are often avoided by women with migraines. This is due to fears of ischemic stroke risk. This study looked at low-dose COCs and stroke risk in women with migraines. Researchers…
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Migraine Prevalence and QALY Loss in Serbia: A Population-Level Stratified Modeling Study.
Migraine is a common health issue in Serbia. This research aimed to understand how many people suffer from migraines. The study looked at different age groups and both sexes. It used data from the 2022 Serbian Census…
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Papilledema is not the point: intracranial pressure dysregulation as a common pathway in migraine and idiopathic intracranial hypertension.
Recent research suggests that migraines and idiopathic intracranial hypertension (IIH) may be linked. The study involved 161 patients with migraines, both with and without aura, and IIH. They were compared to 37…
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Stress, Anxiety, Depression, and Pain Catastrophizing in Migraine: Associations with Disability and Quality of Life.
Migraine is a common neurological condition that affects daily life. This study explored how stress, anxiety, depression, and pain catastrophizing impact migraine severity. Researchers studied 128 patients in…
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Migraine immune cell gene targets and their relationship to psychiatric disorders.
Migraine often occurs alongside psychiatric disorders like anxiety and depression. Researchers studied the genetic connections between these conditions using data from immune cells. They analyzed information from…
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Distinct brain metabolic patterns reflect biological heterogeneity and relate to clinical outcome in chronic migraine with medication overuse.
Chronic migraine with medication overuse (CMwMO) can be very disabling. This condition shows varied responses to treatments and medication withdrawal. Researchers studied brain metabolic patterns in CMwMO patients…
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Blood levels of PACAP in migraine: A systematic review.
The research aimed to understand the role of PACAP in migraines. PACAP is a substance in the blood linked to migraine attacks. The study reviewed existing research to see if PACAP levels differ in migraine patients…
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The effectiveness of non-invasive vagus nerve stimulation in migraine management: a meta-analysis of randomized controlled trials.
Non-invasive vagus nerve stimulation (nVNS) is a new treatment for migraines. This research reviewed several studies to see how effective nVNS is. Researchers looked at its effects on headache days and pain…