Latest Migraine & Headache Research
MigraineMind provides concise summaries, key learning points and links to the original scientific publications behind recently published migraine and headache research. Learn about MigraineMind or read how the research summaries are made.
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Explore focused collections that currently meet MigraineMind’s five-paper quality threshold.
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What Do Vestibular Tests Reveal in Vestibular Migraine?
Vestibular migraine (VM) causes recurrent vertigo but lacks specific diagnostic tests. This study examined three tests: videonystagmography (VNG), caloric testing, and video head impulse test (vHIT). Researchers…
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OnabotulinumtoxinA Improves Sleep Quality in Patients with Chronic Migraine: A Prospective Real-World Study.
months of treatment. Researchers found that sleep quality improved significantly in patients after receiving OBT-A. Specifically, 63% of patients reported better sleep after three months. Patients also experienced…
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Effectiveness of atogepant in migraine with and without medication overuse: Pooled real-world analysis of two independent clinical cohorts.
This study looked at how effective atogepant is for treating migraines. Atogepant is taken once daily at a dose of 60 mg. Researchers combined data from two groups of patients with migraines. One group followed up…
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Cardiometabolic parameters and novel hematological indices in women with migraine.
The research studied 50 women with migraine and 25 healthy controls. It aimed to understand the link between migraine and certain blood indicators. Researchers measured cardiometabolic factors and new blood indices…
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Emerging pharmacological targets in migraine therapy: CGRP and beyond.
Migraine is a common and challenging neurological disorder affecting many people. Current treatments often rely on repurposed medications, leading to frequent treatment failures. Research shows that migraine is not…
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Time from Migraine Onset to Surgery Predicts Postoperative Headache Frequency: A Retrospective Cohort Study.
This study looked at patients who had migraine trigger-site surgery in Taiwan. It aimed to find out if the time between migraine onset and surgery affects outcomes. Researchers analyzed data from 54 patients, mostly…
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Sleep and Migraine Interactions in Episodic and Chronic Migraine: A Hospital-Based Cross-Sectional Study.
Migraine and sleep problems often occur together, affecting many patients. This study looked at 253 migraine patients, including those with episodic and chronic migraines. Researchers measured migraine-related…
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Multimodal 7T MRI reveals subcortical structural, functional, iron accumulation, and glymphatic abnormalities in chronic migraine.
Chronic migraine (CM) is a complex condition that affects many people. Researchers used advanced 7T MRI technology to study brain changes in CM patients. They looked at 62 healthy controls, 62 episodic migraine…
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Right-to-left shunt is associated with reduced cerebral vascular reactivity in migraine patients with aura.
Migraine patients with aura may have a condition called right-to-left shunt (RLS). This study looked at how RLS affects blood flow in the brain. Researchers examined patients at Anhui No. 2 Provincial People's…
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Efficacy and Safety of Cannabinoid-Based Interventions for Low Back Pain and Migraine: A Systematic Review of Randomized Controlled Trials.
Cannabinoid-based treatments are being studied for low back pain and migraines. These conditions cause significant disability in many people. Researchers reviewed several clinical trials to assess their effectiveness…
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Healthcare providers' perceptions and prescribing behaviors of short-term prevention treatment of migraine in the United States.
Healthcare providers (HCPs) play a key role in managing migraine treatments. This study explored HCPs' views and practices regarding short-term prevention (STP) therapies in the US. STP therapies help prevent…
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Considerations for understanding systematic reviews and network meta-analyses in neurological applications: a review and critique in chronic migraine.
Network meta-analysis (NMA) helps compare multiple treatments for chronic migraine. It combines direct and indirect evidence when head-to-head trials are missing. Guidelines exist for conducting and reporting NMAs…
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Early improvements in function with atogepant as assessed by the Activity Impairment in Migraine-Diary: Post hoc analyses of three randomized, phase 3 clinical trials of atogepant for the preventive treatment of migraine.
Atogepant is a new treatment for preventing migraines. This study looked at how it helps improve daily activities. Researchers analyzed data from three large clinical trials. They focused on patient-reported outcomes…
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Factors Impacting the Telephone Follow-Up Response Rate in Patients With Migraine Without Aura: A Cross-Sectional Study of 1299 Females.
The study examined factors affecting how often female migraine patients respond to follow-up calls. Researchers analyzed data from 1299 women with migraine without aura. They found that 63.2% of patients responded…
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Migraines in pregnancy: a prospective study of symptom patterns and obstetric outcomes.
Migraines are common during pregnancy, affecting many women. In a study, 858 pregnant patients were assessed for headaches. Out of these, 546 (63.6%) had migraines, while 312 (36.4%) had tension-type headaches. The…
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CD200/CD200R1 activation alleviates central sensitization in chronic migraine via STAT6.
Chronic migraine (CM) involves a process called central sensitization (CS). This process is influenced by microglial activation in the brain. Researchers studied the CD200/CD200R1 pathway, which helps regulate immune…
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Comparative Efficacy of Acupuncture, Pharmacological Interventions, Sham Acupuncture, and Placebo for Migraine Prevention: A Bayesian Network Meta-Analysis.
This study looked at how well acupuncture, medications, sham acupuncture, and placebo work for preventing migraines. Researchers reviewed 32 randomized controlled trials to gather data. They focused on how these…
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Eleven-Year Diagnostic Delay in Episodic Cluster Headache With a Characteristic International Classification of Headache Disorders, 3rd Edition (ICHD-3) Clinical Pattern: A Case of Migraine Misdiagnosis and Otologic Confusion.
A 31-year-old man suffered from severe headaches for 11 years. His headaches were misdiagnosed as migraines. He experienced intense pain in one eye. This pain lasted 30 to 60 minutes. The headaches happened more than…
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Vitamin D concentrations and neutrophil-to-lymphocyte ratio are associated with disability and pain sensitivity in individuals with migraine: a cross-sectional study.
This study investigated how certain biological markers relate to migraine symptoms. Researchers studied 72 adults diagnosed with migraines. They looked at factors like pain sensitivity, disability, stress, and muscle…
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Analysis of Sleep Quality and Its Associated Factors in Adolescents with Migraine.
This study looked at sleep quality in adolescents with migraines. Researchers assessed 168 adolescents, including 50 healthy controls and 118 migraine patients. They used several questionnaires to measure…