Latest Migraine & Headache Research
MigraineMind provides concise summaries, key learning points and links to the original scientific publications behind recently published migraine and headache research. Learn about MigraineMind or read how the research summaries are made.
Browse migraine research by topic
Explore focused collections that currently meet MigraineMind’s five-paper quality threshold.
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Seasonal Variation and Diurnal Rhythmicity of Migraine Attacks in Patients from a North Indian Tertiary Care Center.
Migraine is a common and painful condition affecting many people. This study explored how migraine attacks vary by season and time of day. Researchers surveyed 120 migraine patients over one year in North India. They…
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Evaluation of Ocular Higher-Order Aberrations in Patients with Migraine: A Comparative Study.
This study examined how migraines affect eye functions, specifically higher-order aberrations (HOAs). Researchers compared 99 migraine patients with 99 healthy individuals. They measured various eye distortions using…
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Flunarizine and cinnarizine in the prophylaxis of vestibular migraine and migraine-associated menière's disease: An 8-month retrospective study.
This study looked at two treatments for vestibular migraine (VM) and migraine-associated Menière's disease (MAMD). These conditions cause frequent vertigo and can severely affect quality of life. Researchers analyzed…
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[Treatment persistence and adherence with botulinum toxin type A and anti-calcitonin gene-related peptide monoclonal antibodies in migraine. (A retrospective cohort study from a specialized headache center)].
This study looked at how well migraine patients stick to treatments. It compared two options: botulinum toxin type A (BTA) and monoclonal antibodies targeting calcitonin gene-related peptide (anti-CGRP mAb)…
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Acute treatment of migraine in children aged 6-11: Real-world analysis of remote electrical neuromodulation (REN).
Migraine affects many children and adolescents, causing significant challenges in their lives. Currently, only one medication is approved for treating migraines in kids aged 6-12. Remote electrical neuromodulation…
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Gut microbiota-derived trimethylamine N-oxide (TMAO) and its association with neuroinflammation in migraine.
Migraine is a common headache disorder linked to neuroinflammation. Recent studies suggest that gut bacteria and their byproducts may play a role. Trimethylamine-N-oxide (TMAO) is one such byproduct. It is produced…
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The Impact of Migraine on School Attendance and Psychosocial Functioning in Children and Adolescents: A Cross-sectional Study.
This study looked at how migraines affect school attendance and psychosocial functioning in kids. Researchers examined 70 children and teens aged 12 to 17. Most participants were girls, and many were in high school…
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[Pituitary adenylate-cyclase activating polypeptide (PACAP)-targeting treatment as a potential migraine prophylactic therapy].
In migraine prevention, new treatments are being explored that target PACAP. Current options include monoclonal antibodies (mAbs) and other specific drugs. Researchers conducted a review of existing literature on…
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The role of Kynurenine-Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) axis in migraine pathophysiology and therapy.
Migraine is a common headache disorder, but its exact causes remain unclear. Researchers have traditionally focused on serotonin, but new studies highlight a different pathway. This pathway involves tryptophan…
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Reduced binaural masking release in women with migraine despite normal hearing: a case-control study.
Migraine is a common neurological disorder that affects many people. This study looked at how migraines impact hearing. Researchers tested 30 women with migraines and 35 healthy women. All participants had normal…
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Expanding the Neurological Phenotype of ZTTK Syndrome: A Case of Recurrent Acute Confusional Migraine.
Acute confusional migraine (ACM) is a rare type of migraine in children. It causes confusion, agitation, and changes in brain activity. This paper discusses a child with ACM and ZTTK syndrome. ZTTK syndrome is a rare…
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Impact of Mediterranean Diet-Based Nutrition Education on Migraine Disability in Adolescents: A Pilot Interventional Study.
This study explored how a Mediterranean diet might help adolescents with migraines. Seventeen young patients participated in a three-month program focused on nutrition education. They learned about the benefits of…
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Engineered Extracellular Vesicles As a New Delivery Platform for Migraine.
Migraine is a complicated neurovascular disorder that is hard to treat. The blood-brain barrier (BBB) complicates treatment options. Current therapies, like CGRP inhibitors, can help but have limitations. They may…
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Development and Evaluation of Rizatriptan Benzoate Orally Disintegrating Tablets for Migraine Treatment.
This study focused on creating a new type of migraine treatment. The researchers developed rizatriptan benzoate (RZT) orally disintegrating tablets (ODTs). These tablets dissolve quickly in the mouth, making them…
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Exploring the complex relationship between vestibular symptoms and migraine: a resting‑state functional MRI study.
This study looked at how vestibular symptoms and migraines relate to each other. Researchers focused on 69 participants with different types of migraines and vestibular issues. They examined whether these symptoms…
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Home-based video-oculography during spontaneous vertigo attacks: A proof-of-concept feasibility study in Ménière's disease and vestibular migraine.
is group recorded usable eye movement data. The study showed that home-based video-oculography is feasible for measuring eye movements during spontaneous vertigo attacks. This method could help improve the diagnosis…
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Twelve-months prospective real-world assessment of effectiveness and safety of eptinezumab in migraine patients difficult-to-treat and naïve to CGRP monoclonal antibodies: results of the French FHU INOVPAIN registry.
This study looked at how effective and safe a drug called eptinezumab is for migraine patients in real life. The research involved 302 patients from a French hospital registry. Most of the patients were women, and…
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The American Headache Society Consensus Statement: Update on integrating new migraine treatments into clinical practice
This paper discusses updated guidance on new migraine treatments for adults. The American Headache Society aimed to include recent research, expert consensus, and patient perspectives. Previous Consensus Statements…
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Migraine: epidemiology and systems of care
Migraine is a neurovascular disorder impacting over 1 billion people globally. Its prevalence leads to significant disability and negative effects on individuals and their families. Employers and society also bear…
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Migraine remains second among the world’s causes of disability, and first among young women: findings from GBD2019
The study highlights migraine as a leading cause of global disability. Migraine ranks second worldwide for disability, especially affecting young women. The Global Burden of Disease 2019 study supports these…