Latest Migraine & Headache Research
MigraineMind provides concise summaries, key learning points and links to the original scientific publications behind recently published migraine and headache research. Learn about MigraineMind or read how the research summaries are made.
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Explore focused collections that currently meet MigraineMind’s five-paper quality threshold.
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Assessment of Cerebral Perfusion Asymmetry in Chronic Migraine Patients Using Intravoxel Incoherent Motion (IVIM)-Derived Pseudodiffusion Coefficient and Perfusion Fraction.
Chronic migraine (CM) affects many people and involves changes in the brain. Researchers studied blood flow in the brain during the interictal phase of CM. They used a special MRI technique called IVIM to measure…
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Beyond pain relief: rethinking sleep outcomes in CGRP-targeted migraine therapy.
CGRP-targeted therapies have changed how we treat migraines, but their impact on sleep isn’t fully clear. This review looks at recent studies on sleep outcomes with these therapies. These treatments include…
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Resistance training for migraine in females: mechanistic review of hormonal, CGRP, autonomic, vascular and nociceptive pathways.
Resistance training (RT) can help reduce migraine frequency in women. Women are more affected by migraines than men, especially after puberty. This is linked to hormonal changes, particularly estrogen levels. The…
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Network localization of regional intrinsic neural activity alterations in migraine and their neurochemical correlates.
Migraine is a common and disabling condition affecting many people worldwide. Researchers studied brain activity in migraine patients using advanced imaging techniques. They reviewed 31 studies involving over 1,200…
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Peptides whose levels change during the attack period in episodic migraine: NETRIN-1 and amylin.
This study explored the levels of two proteins, netrin-1 and amylin, in migraine patients. Researchers looked at 60 patients with episodic migraine and 30 healthy individuals. They measured these protein levels…
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Cognitive impairment in vestibular migraine: a PubMed-based systematic review and meta-analysis.
Cognitive impairment is common in vestibular migraine (VM) patients. This research reviewed studies from 2010 to 2025. The goal was to quantify cognitive issues in VM. Many patients report symptoms like "brain fog"…
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The effectiveness of clinical hypnosis on migraine headache symptoms and pain perception.
This study looked at how effective clinical hypnosis is for migraine relief. Researchers tested a specific hypnotherapy program called HPMA on 40 outpatients in Iran. Participants included those with and without aura…
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Photobiomodulation and Migraine: Mechanisms and Therapeutic Potential.
Migraine is a common and debilitating condition affecting many people worldwide. It involves issues like mitochondrial dysfunction and neuroinflammation. Researchers are exploring photobiomodulation, a noninvasive…
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Systemic immune-inflammation index and prognostic nutritional index in vestibular migraine and Meniere's disease: a retrospective comparison with healthy controls.
This study compared the systemic immune-inflammation index (SII) and prognostic nutritional index (PNI) in patients with vestibular migraine (VM), Meniere's disease (MD), and healthy controls. It included 100…
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Shift work, headache, and migraine in a large cohort of Dutch nurses.
Shift work is common among nurses and may lead to headaches and migraines. This study looked at Dutch nurses to understand this connection better. Nearly 60,000 participants completed surveys in 2011 and over 37,000…
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Central executive network-related neuromagnetic abnormalities in chronic and episodic migraine: a resting-state magnetoencephalography study.
Chronic migraine (CM) is more disabling than episodic migraine (EM). Researchers studied brain activity differences between CM, EM, and healthy controls. They analyzed data from 22 CM patients, 20 EM patients, and 25…
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[Diagnosis and Management of Patients with Migraines and Other Headaches].
Headaches are a common issue for many people. Neurologists often see patients with headaches. It is important to identify the type of headache. Some headaches are primary, like migraines, while others are secondary…
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Efficacy of Combining Conventional Physiotherapy for Migraine With Transcutaneous Stimulation of the Auricular Vagal Nerve or Supraorbital Nerve: Protocol for a Randomized Controlled Trial.
Migraine is a common condition that causes severe headaches and other symptoms. These symptoms can greatly impact a person's quality of life. Conventional physiotherapy helps manage migraines but may not fully…
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Exploring Proximal and Distal Ultrasound-Guided Greater Occipital Nerve Block Approaches in Migraine: A Systematic Review and Meta-Analysis.
This research paper examines the effectiveness of ultrasound-guided greater occipital nerve block (US-GONB) for treating migraines. Researchers analyzed data from twelve studies involving 658 patients. They looked at…
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Long-term safety of CGRP pathway inhibitors in migraine patients with prior cerebrovascular or cardiovascular disease.
CGRP pathway inhibitors are effective treatments for preventing migraines. This study focused on their long-term safety in patients with previous cerebrovascular or cardiovascular diseases. Researchers analyzed data…
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Hemiplegic migraine: genetics and pathophysiology.
Hemiplegic migraine (HM) is a rare type of migraine that can be inherited. It is caused by specific genetic mutations. Researchers study these mutations to understand how they affect brain function. This research…
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Hormonal treatments and migraine characteristics across reproductive stages and transition to menopause: A cross-sectional study.
Hormonal treatments (HTs) are commonly used by women for various reasons. This study looked at how HTs affect migraines in women. Researchers focused on women aged 18-60 with migraines. They wanted to understand HT…
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Static and dynamic functional connectivity of the bilateral insula in patients with migraine without aura: a resting-state fMRI study.
This research studied brain connectivity in patients with migraine without aura. It focused on the insula, a brain region linked to pain and emotion. The study involved 45 patients and 45 healthy controls…
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Correction: Baglioni et al. Non-Pharmacological Treatments in Paediatric Migraine. <i>J. Clin. Med.</i> 2024, <i>13</i>, 1278.
This research paper discusses non-drug treatments for migraines in children. It highlights various approaches that can help manage migraine symptoms effectively. The study reviews techniques like cognitive-behavioral…
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Prescribing patterns of migraine pharmacotherapy in children and adolescents: descriptive study using a large-scale claims database.
This study looked at how migraine medications are prescribed to children and teenagers. Researchers used a large database to analyze claims from April 2012 to March 2025. They focused on patients aged 6 to 17 years…