Latest Migraine & Headache Research
MigraineMind provides concise summaries, key learning points and links to the original scientific publications behind recently published migraine and headache research. Learn about MigraineMind or read how the research summaries are made.
Browse migraine research by topic
Explore focused collections that currently meet MigraineMind’s five-paper quality threshold.
-
Depressive and anxiety symptoms during CGRP-targeted migraine prevention: A systematic review and meta-analysis.
Migraine often occurs alongside depression and anxiety, worsening patients' overall health. This study looked at how CGRP-targeted therapies affect these mental health symptoms. CGRP-targeted treatments are effective…
-
Acupuncture at Zuqiaoyin (GB44) Modulates Regional Brain Activity in Migraine Without Aura: A Resting-State Functional Magnetic Resonance Imaging Study.
Migraine is a common neurological disorder affecting many people. This study examined acupuncture at a specific point called Zuqiaoyin (GB44). Researchers wanted to see how effective this treatment is for migraine…
-
2026 Taiwan guidelines for the acute pharmacologic treatment of migraine in adults.
Recent updates to Taiwan's migraine treatment guidelines reflect new advances in medicine. The Taiwan Headache Society reviewed both pharmacological and non-pharmacological treatments. They used evidence-based…
-
Development and external validation of a migraine analgesic usage (MAU) index for identifying high-severity migraine: A multi-center study.
This study aimed to create a scorecard for identifying severe migraines. It combines two factors: monthly acute medication days and a questionnaire about migraine treatment. Researchers wanted to see if this…
-
Clinical characteristics and exploratory serum biomarker findings in vestibular migraine: a cross-sectional case-control study.
Vestibular migraine (VM) is a common condition that causes dizziness and headaches. Diagnosing VM can be difficult due to overlapping symptoms with other disorders. This study aimed to better understand VM's clinical…
-
Retinal optical coherence tomography angiography findings in the new- onset migraine patients: a prospective case-control study.
This study looked at the eyes of people with new-onset migraines. Researchers used a technique called optical coherence tomography angiography (OCTA) to examine their eyes. They compared 54 migraine patients to 55…
-
Effectiveness of Rimegepant for the Acute Treatment of Migraine Among Participants Using Different Types of Preventive Therapy: Analyses from CONFIDENCE.
This study looked at how well rimegepant works for treating migraines. Researchers focused on patients using different preventive medications. The study involved participants in the United States who had 3-14…
-
Candesartan for Migraine Prophylaxis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This study reviewed the effectiveness of candesartan for preventing migraines. Migraines are common and can severely impact daily life. Many patients struggle with current preventive treatments due to side effects or…
-
Efficacy and Safety of Fremanezumab in Episodic Migraine: A Systematic Review and Meta-analysis.
Fremanezumab is a new treatment for preventing episodic migraines. This research reviewed its effectiveness and safety through a systematic analysis. The study included four clinical trials with 1,764 participants…
-
Retrospective Review of Dual CGRP-Targeted Regimens for Acute and Preventive Treatment of Migraines in a Veteran Population.
A recent study examined the safety and effectiveness of dual CGRP-targeted treatments for migraines. Researchers focused on patients who used both preventive and acute CGRP medications. The study included 89…
-
Anti-CGRP Monoclonal Antibodies in Chronic Migraine: A Position Statement of the Brazilian Academy of Headache and Orofacial Pain.
Chronic migraine (CM) is a serious condition affecting many people. It often comes with other health issues and is hard to treat. Recent treatments include anti-calcitonin gene-related peptide (CGRP) monoclonal…
-
Atogepant modulates brain connectivity in episodic migraine: a longitudinal exploratory fMRI study.
Episodic migraine (EM) is a common and debilitating condition affecting many people. Recent treatments have focused on a substance called CGRP, which plays a role in migraines. Atogepant is a new oral medication that…
-
Vestibular Rehabilitation for Vestibular Migraine: A Systematic Review and Meta-Analysis.
Vestibular migraine (VM) can cause dizziness and balance problems. This research looked at how vestibular rehabilitation (VR) helps adults with VM. Researchers reviewed studies published until May 2025. They followed…
-
Clinical otoneurological differences between vestibular migraine and probable vestibular migraine.
This study examined vestibular migraine (VM) and probable vestibular migraine (PVM) in patients. Researchers aimed to find out how often patients experience hearing loss and balance issues. They looked at data from…
-
Responding With Evidence and Access for Childhood Headaches (REACH) study: A comparative effectiveness trial of cognitive behavioral therapy monotherapy versus combined cognitive behavioral therapy-pharmacotherapy with amitriptyline for the prevention of childhood migraine-The study protocol.
Migraine is a common health issue for children and teens. It causes significant disability and often continues into adulthood. Current recommendations suggest using both medication and cognitive behavioral therapy…
-
Nutritional supplements for migraine prevention: evaluating evidence sufficiency and effect modifiers through network meta-analysis, trial sequential analysis, and meta-regression.
This research looked at how well nutritional supplements can prevent migraines. The study used advanced methods to compare different supplements based on their effectiveness and safety. Researchers gathered data from…
-
Impact of migraine on quality of life and disability: a matched cross-sectional comparative study in a tertiary hospital in Malaysia.
Migraine significantly impacts the quality of life for many individuals. This study compared 100 migraine patients to 100 healthy controls. All participants completed questionnaires assessing their quality of life…
-
The Estrogen-CGRP Axis in Migraine: Neuroimmune Mechanisms, Sex Differences, and Therapeutic Implications.
Migraine is a common disorder that affects many people, especially women. Research shows that estrogen and calcitonin gene-related peptide (CGRP) may play key roles. These two factors interact and influence how…
-
Estradiol and other sex hormone dynamics in menstrual migraine: pathway analysis of hormones in a case-control follow-up study.
Menstrual migraine (MM) is related to changes in sex hormones, especially estradiol. This study aimed to understand how estradiol levels change in women with MM. Researchers examined blood samples from 46 women…
-
Neural Circuit Dysfunctions in Migraine: A Stage-Specific Dynamic Perspective.
Migraine is now seen as a brain disorder with different clinical phases. These phases show how brain circuits change and interact over time. Researchers reviewed studies from 2010 to 2024 to understand this better…