Latest Migraine & Headache Research
MigraineMind provides concise summaries, key learning points and links to the original scientific publications behind recently published migraine and headache research. Learn about MigraineMind or read how the research summaries are made.
Browse migraine research by topic
Explore focused collections that currently meet MigraineMind’s five-paper quality threshold.
-
Comparison of the Effectiveness of Greater Occipital Nerve (GON) Block and Sphenopalatine Ganglion (SPG) Block in the Treatment of Chronic Migraine.
Chronic migraine significantly affects quality of life and can be debilitating. This study compared the effectiveness of greater occipital nerve (GON) block and sphenopalatine ganglion (SPG) block. It involved 50…
-
Evidence of Hypoxia Signaling and Endothelial Activation in Migraine: Relationships Between HIF-1α, VEGF-A, and Arginine Metabolism.
Migraine is a common neurovascular disorder that causes significant disability. This study explored the role of hypoxia signaling and endothelial dysfunction in chronic migraine. Researchers analyzed plasma samples…
-
Peripheral Nerve Blocks in Adolescents with Medically Refractory Migraine: A Retrospective Observational Study.
This study evaluated the effectiveness and safety of peripheral nerve blocks in adolescents. Twenty-eight adolescents with refractory migraines were included in the assessment. The greater occipital nerve and lesser…
-
Exercise & Migraine: Triggers, Prevention, and Management
Exercise has a complex relationship with headache disorders, especially migraines. Physical activity can trigger or worsen acute migraine attacks. However, exercise is also an effective preventive strategy for…
-
Atypical Migraine? Consider Sjögren's: A Diagnostic Insight
Atypical presentations of Primary Sjögren's Syndrome can resemble migraine symptoms. This syndrome often starts with dry mouth and eyes but may also include migraines. A case study describes a 34-year-old woman…
-
Cervical strengthening and stabilization exercises in migraine management: A systematic review.
Patients with migraines often receive referrals for physical therapy, especially with neck pain. Cervical strengthening and stabilization exercises are commonly suggested for these patients. However, the evidence…
-
Allergic diseases in early childhood and their association with migraine: a large-scale retrospective study.
Migraine is a common neurological disorder affecting children. This study investigates the link between allergic diseases and migraine in early childhood. Researchers analyzed electronic medical records from a large…
-
Association of transverse sinus stenosis and dominant venous sinus drainage pattern with chronic migraine: A matched case-control study.
Transverse sinus stenosis (TSS) may be important for chronic migraine (CM). This study included 94 CM patients and 94 matched controls. All participants underwent magnetic resonance venography to assess their venous…
-
Osmophobia in Patients With Migraine: A Systematic Review and Meta-Analysis.
This study examined osmophobia in patients with migraine through systematic review. Researchers analyzed 58 studies involving 22,299 patients to determine osmophobia prevalence. The findings revealed that 48% of…
-
Interictal burden in migraine: a systematic review of conceptual domains and measurement properties of instruments.
Migraine significantly affects individuals during acute attacks and headache-free periods. This research evaluates tools measuring the interictal burden of migraines. Patient-reported outcome measures (PROMs) assess…
-
Wildfire-Sourced PM2.5 and Emergency Department Visits for Migraine and Other Primary Headache.
This study explores the link between wildfire smoke and migraine-related emergency department visits. Researchers focused on fine particulate matter from wildfires, known as PM2.5. The study analyzed data from…
-
[Migraine aura: differential diagnostics between ophthalmology and neurology].
Migraine aura is a significant phase of migraine that deserves attention. About 25% to 35% of people with migraine experience temporary focal neurological symptoms. These symptoms usually develop gradually and spread…
-
Association of Serum hs-CRP and TNF-α With Therapeutic Response to Erenumab for Migraine Prevention: A Registry for Migraine (REFORM) Study.
This study explored the role of inflammatory markers in predicting migraine treatment success. Researchers focused on two markers: high-sensitivity C-reactive protein and tumor necrosis factor-alpha. They studied…
-
Tolerability, safety, and efficacy of atogepant versus topiramate in adults with migraine (TEMPLE): a randomised, head-to-head, phase 3b trial.
This research compares atogepant and topiramate for preventing migraines. Atogepant, a new oral treatment, is a CGRP receptor antagonist. Topiramate is an older, widely used preventive migraine treatment. However…
-
Calcitonin Gene-Related Peptide Monoclonal Antibody Utilization and Treatment Gaps in People with Migraine in Japan: Results from the OVERCOME (Japan) 2nd Study.
Calcitonin gene-related peptide monoclonal antibodies (CGRP mAbs) effectively prevent migraines. However, their use in Japan remains low. The OVERCOME (Japan) 2nd study analyzed CGRP mAb utilization patterns and…
-
Migraine and the unpaid workload: Sex-specific patterns of domestic labor - insights from the SMILE project, a cohort study.
Migraine significantly impacts daily life, especially unpaid domestic labor. This study included 675 adults with migraine and 232 non-migraine controls. Participants completed surveys assessing demographics…
-
A preliminary study on brain functional magnetic resonance imaging in migraine patients with visual aura using visual stimulation.
Migraine is common and often leads to recurrent attacks and poor treatment responses. This condition can greatly affect patients' quality of life. Aura symptoms complicate diagnosis and treatment, increasing…
-
Migraine phenotypes defined by disability, pain topography and autonomic features: association with serum vitamin D status.
Migraine presents a wide range of symptoms and experiences among patients. This research explored how vitamin D levels relate to different migraine types. The study analyzed 95 patients, collecting data on various…
-
Cochlear Functional Changes and CGRP Modulation in a Chronic Nitroglycerin Migraine-Like Rat Model.
Auditory and vestibular symptoms in migraine and inner ear conditions overlap significantly. However, the mechanisms linking migraine biology to inner ear dysfunction are still unclear. This study explored the role…
-
When does empathy help? Patient-perceived physician empathy and migraine severity.
Migraine is a leading cause of disability worldwide. This research explored the link between patient-perceived physician empathy and migraine severity. Two studies involved 131 migraine patients, with various…