Latest Migraine & Headache Research
MigraineMind provides concise summaries, key learning points and links to the original scientific publications behind recently published migraine and headache research. Learn about MigraineMind or read how the research summaries are made.
Browse migraine research by topic
Explore focused collections that currently meet MigraineMind’s five-paper quality threshold.
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Migraine: Epidemiology, Risk Factors, Pathophysiology, and Treatment.
Migraine is a common and disabling brain disorder affecting about 1 billion people. It particularly impacts women and working-age adults. This condition was once thought to be a simple headache, but it’s more…
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Real-world evidence on migraine treatment in routine clinical practice: insights from the Türkiye migraine registry study using artificial intelligence algorithms.
Migraine remains a significant challenge, despite available treatments. Researchers used artificial intelligence to analyze data from the Türkiye Migraine Registry Study. This study included 11,023 adults treated for…
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Lidocaine Combined With Platelet-Rich Plasma for Stellate Ganglion Block in Chronic Migraine: A Multicenter, Prospective, Propensity Score-Matched Cohort Study.
This study looked at a new treatment for chronic migraine. It compared two methods: one using lidocaine alone and the other using lidocaine with platelet-rich plasma (PRP). Researchers enrolled 200 adults with…
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Acoustic voice analysis of women with migraine.
This study looked at how migraine affects women's voices and their quality of life. Researchers recorded voices and surveyed 193 women, including 138 with migraines. They compared these women to a control group of 55…
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Pharmacologic Treatment for Migraine Prevention in Adults Practice Guideline Recommendations: Report of the AAN Guidelines Subcommittee and the American Headache Society.
This research paper offers updated guidelines for preventing migraines in adults. A group of experts reviewed recent studies and evidence. They aimed to create clear recommendations for healthcare providers. The…
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Systematic Review of Pharmacologic Treatment for Migraine Prevention in Adults: Report of the AAN Guidelines Subcommittee and the American Headache Society.
This systematic review examines the effectiveness of medications for preventing migraines in adults. It aims to provide updated guidelines for clinicians treating migraine patients. A multidisciplinary team reviewed…
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Pharmacologic Treatment for Migraine Prevention in Adults Practice Guideline Recommendations: Report of the AAN Guidelines Subcommittee and the American Headache Society.
This research paper updates guidelines for preventing migraines in adults. A panel of experts reviewed recent studies to create these recommendations. They focused on when to start preventive medications for…
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Systematic Review of Pharmacologic Treatment for Migraine Prevention in Adults: Report of the AAN Guidelines Subcommittee and the American Headache Society.
This systematic review examined medications that prevent migraines in adults. It aimed to update guidelines for treating migraine based on recent evidence. A panel of experts reviewed numerous studies on migraine…
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Pharmacotherapy for chronic migraine prevention: a narrative review.
Chronic migraine (CM) is a serious condition affecting 1-2% of people. It causes significant pain and can disrupt daily life. This research reviews various treatments for preventing CM. The authors examined studies…
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Migraine and Work-Disability: New Treatments Reduce Work-Related Burden Among Migraine Population.
Migraine often leads to significant work disability, impacting productivity and quality of life. This study examined how new treatments can help reduce work-related limitations in migraine patients. Researchers used…
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Tracking migraine outcomes over time by age and monoclonal antibody type: a retrospective, single-center, real-world study.
This study looked at how different CGRP monoclonal antibodies (mAbs) help adults with migraines. Researchers tracked 453 patients aged under 50 and over 50. They used four types of mAbs: erenumab, galcanezumab…
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Assessment of Chocolate, Cheese, and Caffeine as Migraine Triggers: A Systematic Review and Meta-Analysis of Patient-Reported Trigger Rates.
Migraine affects about 14%-15% of people worldwide and causes significant disability. Many patients believe that certain foods trigger their migraines, especially chocolate, cheese, and caffeine. However, research…
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OnabotulinumtoxinA for chronic migraine: A real-life multicenter study of 479 patients.
Chronic migraine (CM) is a tough condition to treat, especially with medication-overuse headache (MOH). This study looked at how well onabotulinumtoxin A (BoNT-A) works for CM. Researchers studied 479 Polish patients…
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The microgenderome in migraine: integrating sex hormones, microbial composition, and metabolic profiles into a sex-related framework.
Migraine is a common and painful condition, affecting many people worldwide. Women are more likely to experience migraines, with rates two to three times higher than men. Researchers are exploring how sex hormones…
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Electroacupuncture Improves Nitroglycerin-Induced Generalized Hypersensitivity Associated with a Migraine-Like State and Downregulates the CXCL13/CXCR5 Axis in the Trigeminal Ganglion.
In this study, researchers explored how electroacupuncture (EA) could help migraine symptoms. They used rats to create a migraine-like state by injecting nitroglycerin (NTG). The rats were divided into four groups…
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Deprescribing and Anti-CGRP preventive therapy in medication-overuse headache associated with migraine: pathophysiological rationale and single-center real world evidence.
Medication-overuse headache (MOH) is a common issue for many migraine sufferers. It happens when people take too much medication for migraines, leading to more headaches. This study looked at a new approach to…
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IgG positive food elimination diet altered gut microbiota, decreased zonulin in migraine adults: a pilot dietary intervention trial.
In this study, researchers explored how a specific diet affects migraine patients. They focused on patients with food-specific IgG antibodies. A total of 52 patients followed a diet avoiding IgG positive foods…
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Longitudinal Outcomes of Bilateral and Unilateral Proximal Greater Occipital Nerve Pulsed Radiofrequency in Migraine: A Prospective Randomized Controlled Trial.
This study explored the effects of two different treatments for migraines. Researchers compared unilateral and bilateral greater occipital nerve pulsed radiofrequency (GON-PRF) treatments. They included 187 patients…
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Dopaminergic Dysregulation in Migraine: From Hypothalamic A11 Dysfunction to a Systemic Biobehavioral Phenotype.
Dopamine plays a crucial role in migraine, alongside serotonin and CGRP. It acts as a pain filter and influences premonitory and autonomic symptoms. Researchers reviewed studies from 1976 to 2026 to understand…
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Evidence for Altered Epigenetic Regulatory Machinery in Migraine: A Peripheral Blood Study.
This research studied the genetic factors involved in migraines. Researchers focused on two important genes: CALCA and TRPA1. These genes are linked to the release of a molecule called CGRP, which is crucial in…